Abstract 【Objective】To investigate the sexual dysfunction and risk factors of female patients with condyloma acuminatum after treatment. 【Objective】 The clinical data of 96 female patients with condyloma acuminatum treated in Shaanxi rehabilitation hospital from January 2018 to January 2020 were analyzed retrospectively. The incidence of sexual dysfunction after treatment was analyzed, and the general data such as age, education and bad living habits were counted. The influencing factors of sexual dysfunction after treatment were analyzed by univariate and multivariate logistic regression. 【Results】 A total of 96 patients completed the treatment successfully, and 33 patients had sexual dysfunction after treatment, accounting for 34.38%; 63 cases had no sexual dysfunction after treatment, accounting for 65.62%, which were included in the asexual dysfunction group. Univariate analysis showed that the sexual dysfunction of female patients with condyloma acuminatum after treatment was correlated with education, combined diseases, human papillomavirus 16 (HPV16), drinking, staying up late and the location of skin lesions (P<0.05). Multivariate logistic regression analysis showed that education level (OR=1.147, 95%CI=1.021~1.289), HPV16 (OR=2.517, 95%CI=1.185~5.346), drinking (OR=4.156, 95%CI=1.325~13.036), staying up late (OR=4.153, 95%CI=1.354~12.738), skin lesion site (OR=5.913, 95%CI=2.385~14.660) was an independent risk factor for sexual dysfunction in female patients with condyloma acuminatum after treatment (P<0.05). 【Conclusion】 The disorder of sexual function in female patients with condyloma acuminatum after treatment is closely related to their education, HPV16, drinking, staying up late and the location of skin lesions.
CHEN Bao-shan,GUO Rui-hua. Analysis of Sexual Dysfunction and Risk Factors in Female Patients with Condyloma Acuminatum after Treatment[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(8): 1139-1142.
[1] BADIU D C, MANEA C A, MANDU M, et al. Giant perineal condyloma acuminatum (buschke-lowenstein tumour): a case report[J].Chirurgia,2016,111(5):435-438.
[2] 中华医学会皮肤性病学分会性病学组.尖锐湿疣治疗专家共识(2017)[J].临床皮肤科杂志,2018,47(2):125-127.
[3] HSU T, NAHMIAS Z P, ROSMAN I S, et al. Extragenital condyloma acuminatum in the left axillary vault[J].JAAD Case Rep,2018,4(9):947-949.
[4] BAZOUTI S, ZIZI N, DIKHAYE S. Perianal giant condyloma Acuminatum-Buschke-Löwenstein tumor[J].Presse Med,2019,48(5):584-585.
[5] FAZENDIN E A, CREAN A J, FAZENDIN J M, et al. Condyloma acuminatum, anal intraepithelial neoplasia, and anal cancer in the setting of HIV: do we really understand the risk?[J].Dis Colon Rectum,2017,60(10):1078-1082.
[6] 中华医学会皮肤性病学分会性病学组,中国医师协会皮肤科分会性病亚专业委员会.尖锐湿疣临床诊疗与防治指南(一)[J].中国艾滋病性病,2015,21(2):172-174.
[7] 何丽芬,何志晖.健康女性性功能障碍709例调查及相关因素分析[J].广东医学,2018,39(23):3529-3533.
[8] KHULLAR G, NARANG T, DE D, et al. Recalcitrant giant condyloma acuminatum treated successfully with a novel combination of Mycobacterium indicus pranii immunotherapy and acitretin[J].Int J STD AIDS,2017,28(11):1155-1157.
[9] FURUKAWA S, UOTA S, YAMANA T, et al. Distribution of human papillomavirus genotype in anal condyloma acuminatum among Japanese men: The higher prevalence of high risk human papillomavirus in men who have sex with men with HIV infection[J].AIDS Res Hum Retroviruses,2018,34(4):375-381.
[10] 张海.CO2激光联合中药贞芪合剂治疗肛周尖锐湿疣痊愈率及复发率分析[J].中国地方病防治杂志,2016,31(12):1406.
[11] 陈华,熊琦,陈永艳.尖锐湿疣患者外周血Treg/Th17细胞平衡及相关转录因子的表达[J].中国感染控制杂志,2017,16(12):1120-1125.
[12] 林静,韩永智,李楠, 等.人乳头状瘤病毒感染和复发性尖锐湿疣与细胞免疫水平的关系研究[J].中华医院感染学杂志,2017,27(11):2502-2505.
[13] 赵玉丛,蔡林.男性与女性下体尖锐湿疣的临床特征及流行病学的差异性调查[J].中国性科学,2017,26(3):65-68.
[14] 陈海颜,王之珺,王小兰, 等.女性外阴尖锐湿疣患者人乳头状瘤病毒感染类型与复发的临床分析[J].中华医院感染学杂志,2016,26(15):3528-3530.
[15] 梁艳华,毕超,梁景耀, 等.不同病程尖锐湿疣患者HPV感染和淋巴细胞免疫功能分析[J].中国艾滋病性病,2017,23(12):1138-1140.
[16] 卢忠明,徐萍,剡建平, 等.尖锐湿疣物理治疗后复发高危因素分析及预测模型的建立[J].中国全科医学,2018,21(1):69-71.
2021, Vol. 38 
