胃癌患者行腹腔镜辅助胃癌根治术的疗效及术后并发症发生的危险因素分析

doi:10.3969/j.issn.1671-7171.2021.09.006

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Abstract 【Objective】To analyze the efficacy of laparoscopic assisted radical gastrectomy for gastric cancer and the risk factors of postoperative complications. 【Methods】236 patients with gastric cancer who underwent laparoscopic radical gastrectomy in our hospital from January 2013 to January 2018 were selected. According to the classification standard of postoperative complications of gastric cancer formulated by the Japanese Clinical Oncology Group (JCOG), grade Ⅱ, the above complications were defined as complications, and grade II and below were defined as no complications. The related risk factors of complications after laparoscopic assisted radical gastrectomy were analyzed, and the survival, tumor recurrence or metastasis were followed up and recorded. 【Results】 236 patients with gastric cancer successfully completed laparoscopic assisted radical gastrectomy. A total of 65 cases (27.5%) had postoperative complications, including 14 cases of gastric emptying disorder, 12 cases of intestinal anastomotic leakage, 10 cases of intestinal obstruction, 7 cases of unexplained fever, 5 cases of duodenal stump fistula, 5 cases of pulmonary infection, 4 cases of pancreatic fistula and biliary fistula, 3 cases of anemia, 2 cases of abdominal bleeding and 2 cases of anastomotic leakage, Lower extremity venous thrombosis in 1 case. Univariate analysis showed that complications after laparoscopic assisted radical gastrectomy were associated with age, hypertension, diabetes, digestive tract reconstruction, operative time and intraoperative blood loss/body weight (P<0.05). Multivariate analysis showed that patients older than 60 years old, hypertension, diabetes, Billroth Ⅱ anastomosis, operation time longer than 180 min and intraoperative blood loss/body weight equal to 5 mL/kg were independent risk factors for postoperative complications. The follow-up results showed that 105 patients survived without tumor, 40 patients had tumor recurrence and/or metastasis, 36 patients died related to gastric cancer, 2 patients died of cardiovascular and cerebrovascular diseases and 1 died of accident. 【Conclusion】Laparoscopic assisted radical gastrectomy is effective in the treatment of gastric cancer. The age more than 60 years old, preoperative hypertension, diabetes underlying diseases, long operation time, bleeding during operation and Billroth Ⅱ anastomosis are independent risk factors for postoperative complications.

Key words： Stomach Neoplasms/SU Laparoscopy Gastrectomy Treatment Outcome Postoperative Complications Risk Factors

Received: 16 October 2020

PACS:

R735.2

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	YU Zhi-hui
	WEI Hao-ru

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YU Zhi-hui,WEI Hao-ru. Effect of Laparoscopic Assisted Radical Gastrectomy on Gastric Cancer and Risk Factors of Postoperative Complications[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(9): 1300-1303.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.09.006 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I9/1300

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