Abstract 【Objective】To explore the lymph node metastasis status and its influencing factors in mixed early gastric cancer . 【Methods】A total of 94 patients with mixed early gastric cancer admitted to the First Affiliated Hospital of the Fourth Military Medical University from January 2018 to January 2020 were selected to sort the basic data of patients (gender, age, TNM grade, underlying disease , tumor location, tumor size, tumor number, tumor differentiation, combined ulcers, depth of invasion, etc.). Based on imaging data in combination with pathological results, the patients were evaluated for lymph node metastasis. Thus patients were divided into the metastatic group and non-metastatic group according to whether there was lymph node metastasis. Logistic regression analysis was used to explore the related factors affecting lymph node metastasis in mixed early gastric cancer.【Results】Among the 94 patients with mixed early gastric cancer in this study, 22 patients had lymph node metastasis (the metastasis group), accounting for 23.40%. While 72 patients did not have lymph node metastasis (the non-metastasis group), accounting for 76.60%. The proportion of patients with tumor size≥2 cm, poorly differentiated tumors, combined ulcers and depth of invasion to the submucosa in the metastasis group was higher than that in the non-metastasis group; and the difference was statistically significant (P<0.05). The results of multivariate analysis showed that the tumor size ≥2 cm, poorly differentiated tumor, combined ulcer and depth of invasion to the submucosa in the metastasis group were risk factors for lymph node metastasis in patients with mixed early gastric cancer (P<0.05).【Conclusion】In the metastasis group, patients with mixed early gastric cancer with tumor size ≥ 2 cm, poorly differentiated tumors, combined with ulcers and deep infiltration to the submucosa have a higher risk of lymph node metastasis.
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2021, Vol. 38 
