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Effect of Danhong Injection Combined with Qingxin Huatan Decoction on the Treatment of Phlegm-heat and Heart-disturbing Atrial Fibrillation |
CHANG Lin, XUE Shan-na |
Department of Pharmacy, Shaanxi Provincial Cancer Hospital, Xi'an 710061 |
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Abstract 【Objective】To explore the clinical effect of Danhong injection combined with Qingxin Huatan Decoction in the treatment of phlegm heat disturbing heart atrial fibrillation. 【Methodsv】 A total of 85 patients with phlegm heat disturbing heart type atrial fibrillation treated in Xi'an Daxing hospital from March 2017 to March 2020 was randomly divided into observation group (n=42, routine treatment + Danhong injection + Qingxin Huatan Decoction) and control group (n=43, routine treatment + Danhong injection). The number of episodes of atrial fibrillation, the maximum time limit of ECG P wave (Pmax), P wave dispersion (PD), left atrial diameter, left ventricular ejection fraction (LVEF) and curative effect were recorded before and after treatment. 【Results】 After treatment, the cure rate, effective rate and effective rate of the observation group were higher than those of the control group (Z=15.897,P=0.001<0.05); The number of episodes of atrial fibrillation and left atrial diameter in the two groups were lower than those before treatment, and those in the observation group were lower than those in the control group; LVEF in both groups was higher than that before treatment, and that in the observation group was higher than that in the control group (P<0.05); Pmax and Pd in the two groups were lower than those before treatment (P<0.05); There was no significant difference between the observation group and the control group (P>0.05). 【Conclusion】 Danhong injection combined with Qingxin Huatan Decoction can significantly reduce the attack times of atrial fibrillation and improve ECG related indexes and cardiac function.
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Received: 08 March 2021
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