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| Analysis of Iodine Nutrition with Body Mass Index and Thyroid Related Antibodies in Adolescents in Huizhou |
| PENG Lin-ping, CHEN Li-qiang, LUO Hao-yuan |
| Department of Endocrinology,First People's Hospital of Huizhou, Huizhou 516000, China) |
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Abstract 【Objective】To study the correlation between iodine nutritional status and thyroid related antibody in adolescents in Huizhou. 【Method】A total of 1207 adolescents from 4 high schools in Huizhou were selected randomly in December 2016 and December 2017 respectively, and their urinary iodine concentration, height, weight, serum TSH, FT3, FT4, thyroid peroxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb), and thyrotrophin receptor antibody (TRAb) were detected. 【Results】The median urinary iodine (MUI) of adolescents was 205.93 μg/L in Huizhou region. There was no significant difference in urinary iodine level between boys and girls(P>0.05, Z=-0.97). Urinary iodine level was positively correlated with TPOAb (R=0.42,P<0.001). Serum TSH level was positively correlated with BMI (R=0.24,P<0.01) . There was no significant difference in urinary iodine level between overweight adolescents and normal BMI population(P>0.05,Z=-0.10). Urinary iodine level was significantly higher in first-degree relatives who have history of hyperthyroidism or hypothyroidism of adolescents(P<0.001,Z=-4.91). 【Conclusion】Urinary iodine levels in adolescents may be associated with thyroid autoimmune diseases,however, it does not affect obesity in adolescents. Urinary iodine concentration monitoring is important to adolescents with thyroid disease clustering families.
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Received: 10 May 2019
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2020, Vol. 37 
