Abstract【Objective】To study the therapeutic effect of Chinese medicine (Ovarian Zaoshuai Recipe) combined with Fimotong on follicular growth hormone (FSH), serum inhibin B (INHB) and estrogen (E2) in patients with premature ovarian failure. 【Methods】 A total of 102 patients with premature ovarian failure treated in our hospital from August 2015 to August 2018 were divided into two groups according to different treatment methods. The control group was treated with Fimotong, while the observation group was treated with ovariectomy recipe on the basis of Finmotong. The clinical efficacy of the two groups after treatment was analyzed. 【Results】The total effective rate was 92.16% (47/51) in the observation group and 76.47% (39/51) in the control group. The total effective rate in the observation group was higher than that in the control group (P<0.05). There were no significant differences in FSH, INHB and E2 level between the two groups before treatment (P>0.05). However, 3 and 6 months after treatment, serum INHB and E2 levels of the observation group were significantly higher than those of the control group, and the FSH level in the observation was significantly lower than that in the control group. The differences were statistically significant (P<0.05). There was no significant difference in Kupperman score between the two groups before treatment (P>0.05). While the Kupperman score in the observation group was lower than that in the control group at 3 months and 6 months after treatment. The recurrence rate was 9.80% in the observation group and 33.33% (17/51) in the control group. The recurrence rate in the observation group was lower than that in the control group (P<0.05). 【Conclusion】The treatment of premature ovarian failure with Chinese medicine combined with Western medicine can improve the expression of FSH, INHB, and E2, reduce the course of disease, improve the curative effect, and result in a low recurrence rate.
LU Mei-yan,MA Xiao-hong,AN Pei-xing, et al. Observation of the Curative Effect of Chinese Medicine Combined with Fimotong in the Treatment of Patients with Premature Ovarian Failure[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(12): 1793-1795.
2020, Vol. 37 
