高血压合并房颤患者血清AngⅡ、ALD、hs-CRP及RDW的变化及其意义

doi:10.3969/j.issn.1671-7171.2020.10.023

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】 To investigate the correlation between the changes of serum angiotensin Ⅱ (Ang Ⅱ), aldosterone (ALD), high sensitivity C-reactive protein (hs CRP) and red blood cell distribution width (RDW) in patients with essential hypertension complicated with atrial fibrillation. 【Methods】 Nighty cases of patients with simple primary hypertension (control group) and 140 cases of patients with essential hypertension combined with atrial fibrillation were selected as the observation group. The serum levels of Ang Ⅱ, ALD, hs CRP and RDW were detected, and the left atrial diameter (LAD), left ventricular end systolic diameter (LVESD) and left ventricular end diastolic diameter (LVEDd) were compared between the two groups.【Results】 The levels of AngⅡ, ALD, hs-CRP, RDW and LAD in the observation group were significantly higher than those in the control group (P<0.05); there was no significant difference in LVESD and LVEDd between the two groups (P>0.05). The levels of AngⅡ, ALD, hs-CRP and RDW in patients with persistent atrial fibrillation were significantly higher than those in patients with paroxysmal atrial fibrillation (P<0.05). AngⅡand ALD were positively correlated with LAD (P<0.05), while hs-CRP and RDW levels were not significantly correlated with LAD (P>0.05). 【Conclusion】 The serum levels of AngⅡ, ALD, hs-CRP and RDW in patients with hypertension complicated with atrial fibrillation were significantly higher than those in patients with simple hypertension.

Key words： Hypertension/CO Atrial Fibrillation/CO Angiotensin Ⅱ/BL C-Reactive Protein /BL

Received: 04 April 2019

PACS:

R544.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZOU Jin-Guo
	BING Sen
	CHEN Xiao-qiang
	et al

Cite this article:

ZOU Jin-Guo,BING Sen,CHEN Xiao-qiang, et al. Changes and Significance of Serum AngⅡ, ALD, hs-CRP and RDW in Patients with Hypertension Complicated with Atrial Fibrillation[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1517-1519.

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.10.023 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I10/1517

[1] Yen J, Lin H, Hsu C, et al. Atrial fibrillation and coronary artery disease as risk factors of retinal artery occlusion: a nationwide population-based study[J].Biomed Res Int,2015,25(6):347616.
[2] 裴芳,王新全,陈鹏,等. 血管紧张素Ⅱ1a型受体在不同周龄自发性高血压大鼠血管组织中的表达及其甲基化状态的研究[J].中华高血压杂志,2015,23(3):231-237.
[3] 孙洁静. 红细胞分布宽度在高血压及合并冠心病患者中的变化[J].中国老年学杂志,2015,35(13):3589-3591.
[4] 刘力生. 中国高血压防治指南2010[J].中华高血压杂志,2011,19(8):701-708.
[5] 刘刚. 缬沙坦联合苯磺酸氨氯地平与氢氯噻嗪对高血压伴阵发性房颤患者心功能及血清炎性因子水平的影响[J].医学临床研究, 2018, 35(10):2026-2027.
[6] Lerario MP, Gialdini G, Lapidus DM, et al. Risk of ischemic stroke after intracranial hemorrhage in patients with atrial fibrillation[J].PLoS One,2015,10(12):579-582.
[7] 梁晶,李旭光,王志敏,等. 高血压伴心房颤动患者的血浆血管紧张素Ⅱ水平及其对应用肾素-血管紧张素系统阻滞剂的指导意义研究[J].中国全科医学,2017,20(19):2353-2357.
[8] 赵利群,李旭光,谢力俊,等. 血管紧张素Ⅱ和醛固酮对原发性高血压患者心房颤动的诊断价值[J].上海交通大学学报(医学版),2016,36(12):1732-1735.
[9] 刘建峰,武艺,郝鹏,等. 原发性高血压患者红细胞分布宽度与左心室肥厚的相关性分析[J].山西医科大学学报,2016,47(1):6-9.
[10] 杨悦. 联合检测血浆血管紧张素Ⅱ、醛固酮、肾素、血浆凝集素样氧化低密度脂蛋白受体-1、内皮素-1水平对原发性高血压的临床意义[J].中国卫生检验杂志,2016,26(15):2201-2203.
[11] 李丽君,侯小玲,耿晓雯,等. 不同性别青年肥胖高血压患者醛固酮水平的变化[J].中华高血压杂志,2018,26(1):56-60.
[12] 李敬,华琦,刘建峰,等. 原发性高血压患者左心房内径与红细胞分布宽度的关系[J].首都医科大学学报,2015,36(3):405-409.
[13] 周亚群,丁存涛,孙希鹏,等. 原发性高血压患者红细胞分布宽度、中性粒细胞/淋巴细胞比值与内皮功能关系的研究[J].首都医科大学学报,2018,39(2):292-298.