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| Effect of Target-directed Liquid Therapy Guided by Stroke Volume Variability on Digestive System in Patients Undergoing Colorectal Cancer Surgery |
| ZHANG Lei, SUN Li, HUANG Yi |
| Department of Anus and Intestine Surgery, Zhongshan Hospital, Dalian University 116000 |
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Abstract Objective To investigate the effect of target-directed liquid therapy guided by stroke volume variability on the clinical efficacy and digestive system in patients with colorectal cancer surgery. Methods A total of 142 patients with colorectal cancer who underwent surgery in our hospital were divided into two groups. Patients in the control group received a goal-directed fluid therapy guided by central venous oxygen saturation, and patients in the observation group received target-directed fluid therapy guided by stroke volume variability. The total fluid volume, surgery procedure, gastrin, motilin and complications were compared between the two groups. Results The total fluid volume of the observation group was smaller than that of the control group. The postoperative feeding time, exhaust time and hospitalization time were shorter than the control group, and the difference between the two groups was significant (P<0.05). The gastrin level of the observation group was higher and the motilin level was lower than that of the control group, and the duration of bloating and the recovery time of bowel sounds were shorter as well (P<0.05). The incidence of complications was 14.08% (10 cases out of 71 patients) in the observation group and 32.39% (23 out of 71 cases) in the control group. The difference between the two groups was statistically significant (P<0.05). Conclusion Target-directed fluid therapy guided by stroke volume variability for patients with colorectal cancer surgery can speed up postoperative recovery, improve the recovery of digestive system, and help reduce clinical complications.
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Received: 28 October 2018
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2019, Vol. 36 
