艾司氯胺酮联合七氟醚对口腔手术患者的麻醉效果

doi:10.3969/j.issn.1671-7171.2026.06.027

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1251 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】 To investigate the anesthetic effect of esketamine combined with sevoflurane in patients undergoing oral surgery. 【Methods】 A total of 102 patients who underwent oral surgery from May 2021 to May 2024 were randomly divided into a control group and an observation group, with 51 cases in each group. The control group received esketamine anesthesia, while the observation group received esketamine combined with sevoflurane anesthesia. Surgical indicators, hemodynamics [heart rate (HR), mean arterial pressure (MAP)], sedation and analgesia levels [Ramsay sedation score, visual analogue scale (VAS)], and the incidence of adverse reactions were compared between the two groups. 【Results】 The onset time of anesthesia, extubation time, complete recovery time, and discharge time in the observation group were all shorter than those in the control group (P<0.05). The HR and MAP at 5 min after anesthesia induction (T₁) and immediately after surgery (T₂) in the observation group were lower than those in the control group (P<0.05). The Ramsay score at the time of leaving the operating room was higher in the observation group, while the VAS scores at 10 min and 30 min after recovery were lower than those in the control group (P<0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). 【Conclusion】 Esketamine combined with sevoflurane anesthesia in oral surgery can accelerate recovery, stabilize intraoperative hemodynamics, improve sedation, relieve postoperative pain, and reduce the incidence of adverse reactions.

Key words： Oral Surgical Procedures Sevoflurane Anesthesia

Received: 17 October 2025

PACS:

R782

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	XU Depei
	SUN Lisheng

Cite this article:

XU Depei,SUN Lisheng. Anesthetic Effect of Esketamine Combined with Sevoflurane in Patients Undergoing Oral Surgery[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(6): 976-978.

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.06.027 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I6/976

[1] 辛志军,王宁,曲伟栋,等. 小剂量艾司氯胺酮在全身麻醉下口腔颌面外科短时间手术中的应用[J].口腔医学研究,2023,39(1):46-51.
[2] 赵静,邵建强. 右美托咪定滴鼻与咪达唑仑口服在儿童门诊口腔治疗中的应用效果比较[J].医学临床研究,2022,39(5):768-771.
[3] 韩礼业,高成杰. 不同剂量艾司氯胺酮在甲状腺癌根治术中的麻醉效果及对术后早期情绪反应的影响[J].山东医药,2023,63(2):71-75.
[4] 同鑫,魏莹,谢江帆. 七氟醚复合低剂量艾司氯胺酮麻醉在小儿烧伤扩创削痂生物敷料覆盖手术中的应用[J].河南医学研究,2023,32(21):3885-3889.
[5] 刘清华,李瑞娟. 右美托咪定腰硬麻醉对子宫肌瘤剔除术患者心率、Ramsay评分及不良反应的影响[J].医学综述,2016,22(24):4946-4948.
[6] 谢景连. 瑞芬太尼对剖腹产孕妇的麻醉效果及镇静评分和VAS评分的影响[J].医学临床研究,2020,37(7):1033-1035.
[7] 唐系甜,胡遥,古文珍,等. 集束化护理预防经鼻气管插管全身麻醉口腔颌面外科手术患者鼻翼压力性损伤的效果观察[J].中国实用护理杂志,2023,39(4):248-254.
[8] 张铁成,程菲,赵严礼,等. 鼻咽通气道在颌面外科日间小儿吸入麻醉手术中的临床应用[J].实用口腔医学杂志,2024,40(5):683-686.
[9] 潘桂芳,潘方立. 七氟醚联合右美托咪定在口腔颌面外科正颌手术中的应用[J].实用药物与临床,2020,23(4):329-332.
[10] 赵施施,茆梦,刘莉,等. 艾司氯胺酮对口腔癌患者术后抑郁情绪的影响[J].临床麻醉学杂志,2025,41(3):251-256.
[11] 尹征,王路平,郑叶,等. 七氟醚与丙泊酚全身麻醉对口腔鳞癌手术患者外周血T淋巴细胞亚群水平的影响[J].临床和实验医学杂志,2022,21(12):1336-1339.
[12] 翟晓莉. 艾司氯胺酮联合七氟醚吸入麻醉对腹股沟疝手术患儿血流动力学及苏醒期躁动的影响[J].河南医学研究,2024,33(3):509-512.
[13] 孙强,余伊,刘莉,等. 不插管全凭吸入七氟醚麻醉在患儿口腔日间手术的应用[J].临床麻醉学杂志,2019,35(8):773-775.
[14] 吴波,刘莉,黄晨嘉,等. 艾司氯胺酮与七氟烷对不插管全麻下儿童牙科治疗血流动力学及苏醒质量的影响[J].口腔医学,2023,43(5):456-459.