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| Clinical Efficacy of Yiqi Weixue Capsule Combined with Ferric Carboxymaltose in the Treatment of Iron Deficiency Anemia during Pregnancy |
| HU Fang, WANG Jing |
| Department of Maternity Care, Wuyishan Maternal and Child Health Hospital, Wuyishan Fujian 354300 |
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Abstract 【Objective】To explore the clinical efficacy of Yiqi Weixue Capsule combined with Ferric Carboxymaltose in treating iron deficiency anemia during pregnancy. 【Methods】A total of 97 pregnant women with iron deficiency anemia, who were treated in our hospital between January 2020 and January 2023, were randomly divided into two groups using the method of drawing lots. The observation group (n=48) was treated with Yiqi Weixue Capsule combined with Ferric Carboxymaltose, while the control group (n=49) was treated with Ferric Carboxymaltose only. The clinical efficacy, incidence of adverse reactions, incidence of adverse pregnancy outcomes, and iron metabolism indicators [hepcidin (Hepcidin), serum iron (SI), ferritin (SF), transferrin saturation (TSAT), transferrin (TRF), soluble transferrin receptor (sTfR), ferroportin (FPN), ferritin-like protein (FJV)] and red blood cell parameters [hemoglobin (HGB), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), hematocrit (HCT)] were compared between the two groups after 1 month of treatment. 【Results】After treatment, the observation group showed a higher total effective rate and higher levels of SI, SF, TSAT, and FJV compared to the control group. The levels of Hepcidin, TRF, sTfR, FPN, and the incidence of adverse pregnancy outcomes in the observation group were lower than those in the control group (P<0.05). The levels of HGB, MCH, MCHC, MCV, and HCT in the observation group were higher than those in control group (P<0.05).The incidence of adverse reactions between the two groups was not significantly different (P>0.05). 【Conclusion】The combined therapy is highly effective in treating pregnant women with iron deficiency anemia, significantly improving iron metabolism and red blood cell parameters, alleviating anemia, and reducing adverse pregnancy outcomes. It is safe treatment.
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Received: 19 June 2024
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2024, Vol. 41 
