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| Clinical Value of Predicting Long-term Prognosis of STEMI Patients with White Blood Cell/Average Platelet Volume |
| QI Jiangang, LIU Xiqin |
| Tongchuan Traditional Chinese Medicine Hospital,Tongchuan Shaanxi 727031 |
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Abstract 【Objective】 To investigate the clinical value of white blood cell/mean platelet volume (WMR) in predicting the long-term prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI). 【Methods】 A total of 161 patients with acute STEMI admitted to the Cardiology Department of our hospital from May 2017 to September 2019 were selected and treated with percutaneous coronary intervention (PCI). The patients were divided into a good prognosis group (n=32) and a poor prognosis group (n=129) based on their clinical prognosis. The clinical indicators of the two groups were compared, and multivariate logistic regression analysis was used to analyze the correlation between clinical indicators and long-term adverse prognosis of acute STEMI patients. The receiver operating characteristic (ROC) curve was used to evaluate the value of relevant clinical indicators in predicting the long-term prognosis of acute STEMI patients. 【Results】 The levels of cTnI, LDL-C, WBC, MPV, and WMR in the good prognosis group were significantly lower than those in the poor prognosis group, but the LVEF was higher than that in the poor prognosis group, with statistically significant differences (P<0.05). Multivariate logistic regression analysis showed that WMR, cTnI, MPV, and LVEF were associated with adverse prognosis in patients with acute STEMI (P<0.05), with odds ratios of 3.41, 5.18, 1.18, and 0.91, respectively. ROC curve analysis showed that cTnI had the highest predictive value for adverse prognosis in STEMI patients, significantly higher than WMR, MPV, and LVEF (P<0.01); WMR had a higher predictive value for adverse prognosis in STEMI patients than MPV and LVEF (P<0.05); the optimal diagnostic threshold of WMR was 0.63. Kaplan-Meier survival curve analysis showed that the survival time without major adverse cardiovascular events (MACEs) in the high WMR group was significantly lower than that in the low WMR group (P=0.033). 【Conclusion】 WMR is a potential clinical indicator for predicting the long-term prognosis of STEMI patients and is worthy of clinical reference.
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Received: 27 April 2022
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2024, Vol. 41 
