尿蛋白水平与老年糖尿病患者血糖、血脂水平的相关性分析

doi:10.3969/j.issn.1671-7171.2023.11.016

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (2343 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】To explore the correlation between the level of urinary protein and the level of blood sugar and lipid in elderly patients with diabetes. 【Methods】 The clinical data of 88 elderly patients with diabetes diagnosed and treated in our hospital from June 2020 to June 2022 were retrospectively analyzed. The patients were divided into proteinuria group(n=46) and normal group(n=42) according to their urinary protein level. The general information,blood glucose and blood lipid levels of the two groups were compared. The ROC curve was used to analyze the predictive value of blood glucose and lipid levels on proteinuria in elderly patients with diabetes; Multivariate logistic regression was used to analyze the risk factors of proteinuria in elderly patients with diabetes.【Results】 The proportion of patients with body mass index(BMI) ≥ 24 kg/m²,duration of diabetes ≥ 5 years,hypertension,coronary heart disease,fasting blood glucose(FPG),glycosylated hemoglobin(HbA1c),triglyceride(TG),and total cholesterol(TC) in the proteinuria group were significantly higher than those in the normal group(P<0.05);ROC curve analysis showed that the area under the curve of FPG,HbA1c,TG and TC predicting proteinuria in elderly diabetes patients was 0.841,0.834,0.797 and 0.717,respectively; Multivariate logistic regression analysis showed that BMI ≥ 24 kg/m²,diabetes duration ≥ 5 years,hypertension,coronary heart disease,FPG ≥ 8.640 mmol/L,HbA1c ≥ 7.475%,TG ≥ 1.365 mmol/L,TC ≥ 4.870 mmol/L were risk factors for proteinuria in elderly diabetes patients(P<0.05). 【Conclusion】The level of urinary protein in elderly patients with diabetes is related to the level of blood sugar and blood lipid,and the level of hyperglycemia and blood lipid is related to diabetes nephropathy.

Key words： Diabetes Mellitus Albuminuria Blood Glucose Aged

Received: 29 June 2023

PACS:

R587.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHANG Yanqing
	FAN Xingtao
	REN Weijuan

Cite this article:

ZHANG Yanqing,FAN Xingtao,REN Weijuan. Correlation between Urinary Protein Level and Blood Glucose and Lipid Levels in Elderly Patients with Diabetes[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(11): 1670-1672.

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2023.11.016 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2023/V40/I11/1670

[1] 王建,姜传学,李振军,等. 短时间应用前列地尔联合贝那普利对早期糖尿病肾病患者尿蛋白的影响及治疗效果观察[J].临床误诊误治,2020,33(10):35-40.
[2] 魏垂光,赖小荣. 卡格列净对糖尿病肾病患者尿蛋白及相关指标的影响研究[J].中国全科医学,2021,24(S2):143-146.
[3] 严丽,龚建忠,孔令怡. 2型糖尿病病人踝臂指数与尿微量白蛋白/肌酐比值的相关性分析[J].安徽医药,2019,23(2):313-316.
[4] 刘林华,占锦峰,夏忠彬. 社区人群空腹血糖受损对估算肾小球滤过率的影响研究[J].中国全科医学,2022,26(3):304-307.
[5] 中国老年医学学会老年内分泌代谢分会,国家老年疾病临床医学研究中心(解放军总医院),中国老年糖尿病诊疗措施专家共识编写组. 中国老年2型糖尿病诊疗措施专家共识(2018年版)[J].中华内科杂志,2018,57(9):626-641.
[6] 何传梅,刘锦秀,李慧,等. 高压氧辅助血液透析联合灌流治疗对终末期糖尿病肾病患者肾功能及免疫炎性因子的影响[J].中华航海医学与高气压医学杂志,2021,28(4):460-463.
[7] 宋微,李虹怡,吕洪波. 血清miR-21-3p、IL-18水平对重症急性胰腺炎患者急性肾损伤的预测价值[J].山东医药,2022,62(1):20-24.
[8] 夏阳阳,顾天伟,蒋春明,等. 2型糖尿病患者发生慢性肾脏病的危险因素及与肥胖的相关性研究[J].中华糖尿病杂志,2022,14(2):140-146.
[9] 刘入箐. 2型糖尿病合并慢性肾脏病肾脏病理与临床特点[J].陕西中医,2021,42(S1):42-43.
[10] 蒋飞霞,苏宏业,潘海林,等. 2型糖尿病患者规范治疗后合并糖尿病视网膜病变及糖尿病肾病的情况及其影响因素[J].广西医学,2018,40(7):775-778.
[11] 李正东,张任. 糖尿病肾病的危险因素及瑞舒伐他汀的作用效果[J].国际泌尿系统杂志,2019,39(3):515-518.
[12] 刘培健,王玉林. 老年冠心病合并糖尿病患者尿微量白蛋白水平与冠状动脉病变的关系[J].中华老年医学杂志,2019,38(6):617-619.
[13] 岳晓冬,沈金华,黄爱民,等. 50～60岁社区人群白蛋白尿发生率及其影响因素调查研究[J].中国全科医学,2020,23(23):2987-2990.
[14] 段建芳,王艳妮,金凤钟,等. 糖尿病肾病和血糖控制的关系及相关危险因素分析[J].中华老年多器官疾病杂志,2018,17(1):34-38.
[15] 陈馨韵,尹清华,付平. 脂代谢紊乱在糖尿病肾病发病机制中的研究进展[J].中华肾脏病杂志,2021,37(9):771-778.
[16] 邓婷婷. 糖尿病肾病患者血脂异常与尿蛋白关系研究[J].中国中西医结合肾病杂志,2019,20(6):527-529.
[17] 马世兴,李西胜. 舒洛地特联合缬沙坦治疗糖尿病肾病的疗效及对患者肾保护作用和糖脂代谢的影响[J].海南医学,2022,33(18):2333-2336.