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| Application of Combined Thoracic and Laparoscope in Elderly Esophageal Cancer and Observation of Short-Term Postoperative Recovery |
| ZHANG Pu, XI Pan |
| Department of Thoracic and Cardiovascular Surgery, No.215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000 |
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Abstract 【Objective】 To study the application and short-term postoperative recovery of thoracic and laparoscopic combined treatment for elderly patients with esophageal cancer. 【Methods】 Seventy patients aged 60 to 80 who were treated with esophageal cancer in our hospital from July 2016 to July 2018 were selected and randomly divided into observation group and control group with 35 patients in each group. The observation group was treated with chest and laparoscope combined treatment, while the control group was treated with traditional surgery, The operation time, intraoperative bleeding volume, number of lymph node dissection, extubation time and hospitalization time were compared between the two groups. The 1-year survival was compared between the two groups, and the T cell population in venous blood was measured before and after operation to analyze the immune function of the two groups. Comparisons of postoperative complications. 【Results】 The amount of bleeding during operation in the observation group was significantly less than that in the control group (P<0.05), the time of extubation after operation was significantly lower than that in the control group (P<0.05), and the length of hospitalization after operation was significantly shorter than that in the control group (P<0.05). There was no significant difference in the length of operation and the number of lymph nodes cleared between the two groups (P>0.05). There was no significant difference in cell group and NK cell content (P>0.05). On the 7th day after operation, the levels of CD4+, CD4+/CD8+ and NK cell in the control group were significantly lower than those in the observation group (P<0.05); 2 cases in the observation group were lost, and 1 case in the control group was lost. The 1-year survival rate in the observation group was 82.86% (29/35), and 80.00% (28/35) in the control group. There was no significant difference in 1-year survival rate between the two groups. The total incidence of complications in the observation group was 11.43%, which was significantly lower than that in the control group 31.42% (P<0.05). 【Conclusion】 Compared with traditional surgery, thoracic and abdominal combined radical esophagectomy for elderly esophageal cancer has better clinical efficacy, faster recovery time, lower complication rate and stronger immunity, which is worthy of clinical promotion.
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Received: 18 October 2019
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[1] 司保达, 雷树林, 孙凤林,等. 胸腹腔镜联合食管癌根治术并付诸术后化疗治疗食管癌23例临床分析[J].中国实用医药, 2017, 12(9):43-44.
[2] 王军岐, 杨智, 付小伟,等. 胸腹腔镜联合食管癌根治术治疗老年食管癌的临床疗效及预后分析[J].现代生物医学进展, 2015, 15(15):2888-2890, 2903.
[3] 张国超, 薛奇. 胸腹腔镜联合手术之一[J].中华胃肠外科杂志, 2018, 21(8):883-885.
[4] 凌建华. 胸腔镜与开胸手术治疗早期食管癌的临床疗效观察[J].四川医学, 2014, 35(5):569-571.
[5] 梅越.湖北省丹江口市居民食管癌患病危险因素的病例-对照研究[J].环境与职业医学, 2019, 36(5):445-451.
[6] 姚圣, 刘灿辉, 李宗杰,等. 胸、腹腔镜联合治疗高龄(＞75岁)食管癌的优势研究[J].中国微创外科杂志, 2015, 15(12):1069-1071.
[7] 王晓骏, 张铸, 孙清超. 胸腹腔镜联合下食普癌切除术与开放手术疗效对比的Meta分析[J].世界华人消化杂志, 2014, 22(3):375-382.
[8] 苏文杰. 胸腹腔镜联合手术治疗老年食管癌的临床疗效及安全性观察[J].中国当代医药, 2017, 2(24):55-57.
[9] 姚斓, 王燕嬉, 张伟. 老年肺癌患者外周血T淋巴细胞亚群和自然杀伤细胞的临床及意义[J].中国老年学, 2016, 36(4):860-861.
[10] 牛伟, 孔双. 单腔气管插管全身麻醉应用于二氧化碳气胸下胸腔镜食管癌根治术的麻醉效果研究[J].中国内镜杂志, 2018, 24(2):57-62. |
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2021, Vol. 38 
