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| Factors Influencing Early Death in Patients with Severe Heart Failure Treated by Continuous Renal Replacement Therapy |
| JI Li-hua, LU Feng |
| Department of Critical Care Medicine, Xingyuan Hospital of Yulin, Yulin Shaanxi, 719000 |
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Abstract 【Objective】To analyze the factors affecting early death in patients with severe heart failure with CRRT. 【Methods】A total of 100 patients with severe heart failure who underwent CRRT were enrolled. The mortality of patients treated for 28 days was observed. The patients were divided into death group and survival group according to whether they died. Patient clinical case data were collected and the influencing factors of death was analyzed. 【Results】 Among the 100 patients, 46 patients died, with a mortality rate of 46.0%, of which 34.0% (34/100) died within 14 days. Among the death group and the survival group, there were significant differences in the proportion of systemic inflammatory response syndrome (SIRS), sepsis, mean arterial pressure, base excess (BE), acute physiology and chronic health score (APACHE Ⅱ), sequential organ failure assessment score (SOFA), pH, N-terminal brain natriuretic peptide (NT-proBNP) level, time to start treatment and time to reach negative fluid balance after treatment ( P <0.05).Multivariate regression analysis showed that Sirs, Sepsis, mean arterial pressure, pH, start time of treatment, SOFA score were independent influencing factors of death ( P <0.05). CRRT patients of severe heart failure with SIRS, Sepsis, mean arterial pressure≤60mmHg, pH≤7.35, SOFA score > 10 had poor prognosis.【Conclusion】There are many influencing factors of death within 28 days in patients with severe heart failure receiving CRRT. Patients with SIRS, Sepsis, mean arterial pressure ≤ 60mmHg, pH ≤ 7.35, SOFA score > 10, and starting treatment time > 24h were risk factors for death within 28d.
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Received: 29 October 2020
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2021, Vol. 38 
