|
|
Application Value of Magnetic Resonance Diffusion Tensor Imaging in the Selection of Surgical Segments and Evaluation of Curative Effect of Multilevel Cervical Spondylotic Myelopathy |
CHEN Yao-xin, LI Song-bo, LIU Xian-yin, et al |
Dongguan People's Hospital/Dongguan People's Hospital affiliated to Southern Medical University, Dongguan Guangdong 523018 |
|
|
Abstract 【Objective】 To investigate the application value of diffusion tensor imaging (DTI) in the selection of surgical segments and the evaluation of curative effect of multilevel cervical spondylotic myelopathy.【Methods】 From February 2018 to February 2019, 30 patients with multilevel cervical spondylotic myelopathy were selected The severity of spinal stenosis was graded according to T2WI sequence standard. The apparent diffusion coefficient (ADC) and anisotropy (FA) values of each segment of spinal cord were obtained based on the results of DTI. The responsible segment of cervical spinal cord function damage was determined, and then cervical decompression surgery was performed. JOA score, NDI score and SF-36 quality of life score were recorded before operation, 6 months and 12 months after operation were recorded respectively. Post-operation X-ray film and CT were reviewed to understand the situation of internal fixation. MRI scan and DTI were reviewed at 6 and 12 months after operation, and relevant image data were collected. The changes of ADC value and FA value of spinal cord before and after operation were compared, and the correlation between ADC value and JOA score, NDI score and SF-36 quality of life score was analyzed. 【Results】 There were statistically significant differences in JOA score, NDI score, SF-36 score, ADC value and FA value before operation, 6 months after operation and 12 months after operation (P<0.05). JOA score and SF-36 score were negatively correlated with ADC value, and positively correlated with FA value (P<0.05). The NDI score was positively correlated with ADC value, and negatively correlated with FA value (P<0.05). 【Conclusion】 For patients with multilevel cervical spondylotic myelopathy, the decrease of FA value, the increase of ADC value, the gradual decrease of JOA score, the gradual increase of NDI score, and the decrease of SF-36 score of quality of life indicate that the more serious the cervical spinal cord lesion, the more serious the neurological dysfunction, and the worse the quality of life.
|
Received: 05 August 2020
|
|
|
|
|
[1] Tetreault LA , Karpova A , Fehlings MG . Predictors of outcome in patients with degenerative cervical spondylotic myelopathy undergoing surgical treatment: results of a systematic review[J].Eur Spine J,2015, 24(2):236-251. [2] 蔡汉寿,刘涛,周洁, 等.磁共振弥散张量成像在脊髓型颈椎病中的临床应用研究[J].山西医药杂志,2016,45(9):1011-1013. [3] 黄波,刘彪,黄伟兰, 等.磁共振弥散张量成像诊断轻度脊髓型颈椎病的价值[J].中国CT和MRI杂志,2015,13(3):16-18. [4] Denaro V , Longo UG , Berton A , et al. Cervical spondylotic myelopathy: the relevance of the spinal cord back shift after posterior multilevel decompression. A systematic review[J].Eur Spine J,2015, 24(7):832-841. [5] Aaron Y , Rubin DT , Julian P, et al. Burden of ulcerative colitis on functioning and well-being: a systematic literature review of the sf-36 health survey[J].J Crohns Colitis,2020,12(5):600-609. [6] Pennings JS , Khan I , Davidson CA , et al. Using PROMIS-29 to predict neck disability index (ndi) scores using a national sample of cervical spine surgery patients[J].Spine J,2020, 20(8):28-31. [7] Fujiwara H , Makino T , Yonenobu K , et al. Correlations and time-dependent changes of upper arm performance tests, the Japanese Orthopaedic Association score, and a newly developed patient-based outcome measure : the Japanese Orthopaedic Cervical Myelopathy Questionnaire.[J].Bone Joint J,2016, 98-B(7):990-996. [8] 魏巍,张俊祥.磁共振扩散张量成像在脊髓型颈椎病研究中的进展[J].中华全科医学,2015,13(9):1508-1510. [9] 倪丰,丁阳,唐天泽, 等.磁共振扩散张量成像评估早期脊髓型颈椎病的价值[J].江苏医药,2017,43(10):700-702. [10] 王志军, 马俊丽, 段丽娜,等. 磁共振弥散张量成像在纹状体梗死后黑质继发损伤诊断中的应用[J].宁夏医科大学学报, 2018, 40(8):37-40+44. [11] 王琨, 陈士跃, 陈智, 等. 弥散张量成像参数比值对脊髓型颈椎病临床症状及预后的评估价值[J].第二军医大学学报, 2015, 36(3):268-275. [12] 宋彦澄,康立清,申沧海,等.颅脑fMRI及脊髓弥散张量成像对脊髓型颈椎病患者术后脊髓功能恢复的预测价值分析[J].中华物理医学与康复杂志,2019,41(9):651-656. [13] 丁俊, 陈基明.扩散张量成像在轻度脊髓型颈椎病诊断中的价值[J].皖南医学院学报, 2017, 36(3):270-273. [14] 陈峰,余永强.磁共振张量成像在脊髓型颈椎病中的应用进展[J].安徽医药,2015,7(8):1438-1441. [15] 李翔, 陆瓞骥, 胡勇.磁共振弥散张量成像对脊髓型颈椎病患者术后神经功能恢复的预测作用[J].中国脊柱脊髓杂志, 2019, 29(5):385-393. [16] 涂灿, 汪建华, 廖海波,等. 磁共振扩散张量成像对脊髓型颈椎病的诊断价值[J].医学影像学杂志, 2016, 26(3):19-22. [17] Jones JGA, Cen SY, Lebel RM, et al. Diffusion tensor imaging correlates with the clinical assessment of disease severity in cervical spondylotic myelopathy and predicts outcome following surgery [J].Am J Neuroradiol,2012,34(2) :471-478. [18] Chun Yi W,Jiao Long C, Liu H S, et al. Is diffusion anisotropy a biomarker for disease severity and surgical prognosis of cervical spondy lotic myelopathy[J].Radiology,2014,270(1) :197-204. |
[1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(8): 1245-1247. |
|
|
|
|