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| Comparative Study on Effects of Different Concentrations of Sufentanil Combined with Low-dose Ropivacaine Intrathecal Injection on Labor Analgesia and Outcomes of Mother-infant |
| TANG Hui, HE Hong |
| Changning District Maternal and Child Health Hospital,Shanghai 200051 |
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Abstract 【Objective】 To observe the effects of different concentrations of sufentanil combined with low-dose ropivacaine intrathecal injection on labor analgesia and maternal and infant outcomes. 【Methods】 All 150 maternal women who had natural childbirth in our hospital received intrathecal injection of sufentanil combined with low-dose ropivacaine. According to the concentration of sufentanil, they were divided into group A, group B and group C, indicating sufentanil administration at concentrations of 3μg, 5μg, and 7 μg, respectively. The anesthetic effects of the three groups were recorded and the differences of maternal and neonatal outcomes among the three groups of were compared. 【Results】 The VAS scores and Ramsay scores in the order of group A-group B-group C at 1h and 4h after anesthesia showed trend from high to low and the differences among the three groups were statistically significant (P<0.05). The levels of SBP and HR at 4 h after anesthesia in the three groups showed the highest in group A and the lowest in group B, with group C in the middle. The difference was statistically significant (P<0.05). Among three groups, there was no significant difference in the incidence of neonatal aspiration pneumonia, intracranial hemorrhage and Apgar score after birth (P>0.05). The incidence of nausea, headache and urinary retention in group A and group B was lower than that in group C (P<0.05). 【Conclusion】 Intrathecal injection of 5 μg sufentanil combined with low-dose ropivacaine has good effect in labor analgesia, little effect on maternal hemodynamics, and low complication rate , which shows good application value.
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Received: 20 June 2019
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2020, Vol. 37 
