罗哌卡因神经阻滞方案在神经外科开颅手术中的应用价值

doi:10.3969/j.issn.1671-7171.2020.01.029

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Abstract 【Objective】To explore the clinical value of ropacaine nerve block in neurosurgery craniotomy.【Methods】A total of 98 patients who underwent carniotomy from October 2016 to December 2017 were randomly divided into group A and group B, with 49 cases in each group. Group A received ropacaine nerve block combined with intravenous general anesthesia, while group B only received intravenous general anesthesia. The heart rate (HR), mean arterial pressure (MAP), bispectral index (BIS) at different time points were recorded; postoperative pain (VAS) score, adverse reactions, serum substance P and serotonin (5-HT) before and after surgery were compared in the two groups. 【Results】At the time of T0~T3, there were no significant differences in values of HR, MAP and BIS between group A and the group B (P>0.05). The VAS scores at 4 h, 12 h, and 24 h after surgery in the observation group were significantly lower than those in the control group; and the difference were statistically significant (P<0.05). At 24 hours after operation, serum levels of substance P and 5-HT in group A were significantly lower than those in group B (P<0.05), though there were no significant difference before surgery. The incidence of adverse reactions in patients of group A was 6.12% (3/49) and that of group B was 12.24% (6/49), which did not show statistically significant (χ²=1.101,P=0.294>0.05).【Conclusion】 The use of ropacaine nerve block in neurosurgery craniotomy is beneficial to reduce postoperative pain and decrease serum substance P and 5-HT levels.

Key words： Craniotomy Amides/TU Nerve Block/ME

Received: 04 November 2018

PACS:

R651.1

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	Articles by authors
	QIU De-liang
	ZHANG Qiang
	ZHAO Song-bo

Cite this article:

QIU De-liang,ZHANG Qiang,ZHAO Song-bo. Application of Ropacaine Nerve Block in Neurosurgery[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(1): 92-94.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.01.029 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I1/92

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