|
|
|
| Study on Cognitive Impairment and Influencing Factors in Patients with Sleep Disorders and Depression |
| GU Hai-ping, SUN Ya-ming |
| Department of Neurology, Zhangjiagang Hospital of Traditional Chinese Medicine,Jiangsu Province 215600, China |
|
|
|
|
Abstract 【Objective】To investigate the cognitive impairment and influencing factors in patients with sleep disorders and depression. 【Methods】A total of 160 patients with sleep disorders in our hospital from November 2014 to September 2016 were enrolled in this study. Among them, 60 patients with depression were treated as group A and 100 patients with simple sleep disorder as group B. Tests with repetitive neuropsychological status (RBANS) were used to evaluate the cognitive function of the two groups. The factors related to the cognitive impairment were explored by multivariate regression analysis method. 【Results】 The immediate memory, breadth of vision, speech function, attention, time- delayed memory and the total score of RBANS in group A were significantly lower than those in group B. the differences were statistically significant (P<0.05). The detection rate of cognitive impairment in group A was 46.67% (28/60), which was significantly higher than that in group B 7%(7/100). The difference was statistically significant (P<0.05). Carotid stenosis, prolonged course of sleep disorders and depression were independent risk factors for cognitive dysfunction in patients with sleep disorders (OR=2.296, OR=1.574, OR=1.309,P<0.05). 【Conclusion】Carotid stenosis, prolonged course of sleep disorders and depression are independent risk factors for cognitive dysfunction in patients with sleep disorders. Sleep disorders associated with depression will further increase the cognitive impairment of patients, so we must pay attention to the treatment of patients with depression.
|
|
Received: 08 June 2018
|
|
|
|
|
|
[1] 周玉英, 李向丽, 潘虹. 抑郁症睡眠障碍患者中医辨证施护效果观察[J].西部中医药, 2015, 28(7):149-151.
[2] Bora E, Pantelis C. Meta-analysis of cognitive impairment in first-episode bipolar disorder: comparison with first-episode schizophrenia and healthy controls[J].Schizophr Bull,2015, 41(5):1095-1098.
[3] 付伟, 姜超, 张晶,等. 应用圆分布法分析某院精神疾病季节分布特征[J].南昌大学学报(医学版), 2018, 58(1):85-87.
[4] 陈林, 张建凯, 赵蕊,等. 星状神经节阻滞对老年骨科手术患者术后早期认知功能的影响[J].中国基层医药, 2018, 25(6):701-704.
[5] 张保华,谭云龙,张五芳,等.重复性成套神经心理状态测验的信度、效度分析[J].中国心理卫生杂志, 2008, 22(12):865-869.
[6] 张作记.行为医学量表手册[M].北京:中华医学电子音像出版社, 2005: 214-215.
[7] 张丽文, 武兵, 王秀梅. 三种亚型轻度认知功能损害横向对比研究[J].卒中与神经疾病, 2015, 22(3):144-147.
[8] 李强, 陈敏, 杨泰. 抑郁症发病机制的研究进展[J].神经疾病与精神卫生, 2016, 16(5):524-527.
[9] 郭晓杰, 田峰. 抑郁症患者认知功能及相关影响因素研究进展[J].中国药物与临床, 2016, 16(3):368-370. |
|
|
|
2019, Vol. 36 
