|
|
Predictive Value of Dynamic Enhanced Magnetic Resonance Imaging Combined with Laboratory Examination in Patients with Undifferentiated Arthritis |
ZHANG Hao |
Department of Radiology, the People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, 830001 |
|
|
Abstract 【Objective】To explore the effect of dynamic contrast-enhanced magnetic resonance combined with laboratory tests on the prognosis of patients with undifferentiated arthritis (UA). 【Methods】The clinical data of 180 patients with UA admitted in our hospital from April 2013 to April 2017 were selected. According to the follow-up results whether RA was developed, they were divided into RA group (n=78) and non-RA group (n=71). The data of the remaining 31 patients were not completely excluded. All patients underwent dynamic contrast enhanced magnetic resonance (MRI) and laboratory tests. The indexes of dynamic enhanced MRI and related laboratory indexes were compared between RA group and non-RA group. The diagnostic efficacy of dynamic enhanced MRI in predicting the outcome of UA to RA was analyzed.【Results】There was no significant difference in the proportion of (TTP), rheumatoid factor (RF) positive between the two groups at peak time (P>0.05). In the RA group, the relative RELENH, MAXENH, MAXRELENH, WASHIN, AREACURV, ESR, CRP, ACCP positive and MCV positive were significantly different (P<0.05). AREACURV had the highest sensitivity (96.0%), and AUC max. of WASHIN (0.955), CRP specificity max.(89.6%) and AUC of ACCP positive max.(0.972) had the highest diagnostic efficacy.【Conclusion】Dynamic contrast-enhanced MRI and laboratory related indexes can predict the outcome of UA to RA and can guide early diagnosis and treatment.
|
Received: 21 May 2018
|
|
|
|
|
[1] Wevers-de Boer KV. Determinants of reaching drug-free remission in patients with early rheumatoid or undifferentiated arthritis after one year of remission-steered treatment[J].Rheumatology,2015,54(8):1380-1384. [2] 王林,杨惠民,李贞玉,等.类风湿关节炎中医证型与血浆D-二聚体水平的临床观察[J].环球中医药,2015,8(2):134-137. [3] 李会侠.动态增强磁共振滑膜最大强化斜率对手未分化性关节炎转归的预测价值[J].中华医学杂志,2016,96(41):3315-3318. [4] 柳洋,朱跃兰,侯秀娟,等.芍甘附子汤加味对胶原诱导性关节炎大鼠滑膜血管新生相关因子表达的影响[J].环球中医药,2015,8(6):692-696. [5] Yiannopoulos G,Daoussis D,Melissaropoulos K, et al. Evolution of undifferentiated arthritis: a ten-year experience from the early arthritis clinic of a tertiary care hospital[J].Clin Exp Rheumatol,2015,33(3):341-346. [6] 周云龙,谢侃,许益,等.颈椎类风湿性关节炎诊治体会[J].中华骨与关节外科杂志,2017,10(1):13-17. [7] 黄文波,马占忠,肖凤金,等.抗环瓜氨酸肽抗体、类风湿性因子和红细胞沉降率联合检测对类风湿性关节炎的诊断意义[J].中华临床医师杂志(电子版),2017,11(6):1055-1057. [8] 李会侠,安颖颖,雷新玮,等.MRI动态增强时间-强度曲线在手未分化性关节炎向类风湿性关节炎转归预测中的价值[J].国际医学放射学杂志,2018,41(1):3-6,26. [9] 白毓,何建平.动态增强磁共振成像在判断未分化关节炎转化为类风湿关节炎的应用价值[J].山西医药杂志,2017,46(7):768-770.[10] 孙雁,张炳,季涛等.动态增强MRI对手部类风湿性关节炎活动性的诊断价值[J].中国临床医学影像杂志,2017,28(3):208-211. [11] 李东超,温贵如,王辉,等.骨通贴膏联合温针灸对老年类风湿关节炎患者红细胞沉降率、C-反应蛋白及关节功能的影响[J].河北中医,2017,39(7):1011-1015. [12] Sigari N,Moghimi N,Shahraki FS, et al. Anti-cyclic citrullinated peptide (CCP) antibody in patients with wood-smoke-induced chronic obstructive pulmonary disease (COPD) without rheumatoid arthritis[J].Rheumatol Int,2015,35(1):85-91. [13] 赵万辉,王泽筠,亓琳,等.抗CCP抗体和抗MCV抗体等多种检测对类风湿性关节炎的诊断价值[J].检验医学,2017,32(11):975-978. |
[1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2018, 35(9): 1742-1744. |
|
|
|
|