Abstract:【Objective】 To analyze the composition and clinical data of urinary calculi in patients from Turpan region, clarify the compositional characteristics and distribution rules of urinary calculi in this area, and provide a basic reference for clinical prevention and treatment. 【Methods】 A retrospective analysis was conducted on the clinical data of 118 patients with urinary tract stones admitted to the department of urology, Turpan People's Hospital, from June 2024 to October 2025. The stone compositions were detected using infrared spectroscopy. The overall distribution characteristics of stone components were analyzed, and comparisons were made regarding the detection rates of stone components, the sites of stone occurrence between different genders, and the distribution of major stone components across different age groups. 【Results】 After excluding 1 unqualified specimen, 117 valid samples were included. Calcium oxalate was the main component of the stones, with the detection rates of calcium oxalate monohydrate (76.07%, 89 cases), carbonate apatite (40.17%, 47 cases), and calcium oxalate dihydrate (37.61%, 44 cases), which were all higher than 30%. The detection rate of calcium oxalate monohydrate in females (87.50%) was significantly higher than that in males (70.13%), with a statistically significant difference (P<0.05). Mixed stones were the main type (58.97%), of which the most common combination was calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite (34.78%). Among simple -component stones, calcium oxalate monohydrate was dominant (68.75%). Patients were mainly aged 31-60 years (71.79%), and ureteral stones accounted for the highest proportion (68.38%) in the location of stone occurrence. There were no statistically significant differences in age distribution and stone location between different genders (P>0.05). 【Conclusion】 Urinary calculi in Turpan region are mainly composed of calcium oxalate, with a high proportion of mixed stones. The incidence characteristics are closely related to the local hot and arid climate and dietary habits. Individualized prevention and treatment plans should be formulated clinically based on stone composition and patient characteristics.
[1] 叶章群.泌尿系结石研究现况与展望[J].中华实验外科杂志,2005,22(3):261-262. [2] ROMERO V, AKPINAR H, ASSIMOS D G. Kidney stones: a global picture of prevalence, incidence, and associated risk factors[J].Rev Urol,2010,12(2/3):e86-e96. [3] SOROKIN I, MAMOULAKIS C, MIYAZAWA K, et al. Epidemiology of stone disease across the world[J].World J Urol,2017,35(9):1301-1320. [4] 曾国华,麦赞林,夏术阶,等.中国成年人群尿石症患病率横断面调查[J].中华泌尿外科杂志,2015,36(7):528-532. [5] 陈楠.重视肾结石的诊断及内科治疗[J].中华肾脏病杂志,2004,20(5):380-381. [6] TRINCHIERI A, OSTINI F, NESPOLI R, et al. A prospective study of recurrence rate and risk factors for recurrence after a first renal stone[J].J Urol,1999,162(1):27-30. [7] JOHRI N, COOPER B, ROBERTSON W, et al. An update and practical guide to renal stone management[J].Nephron Clin Pract,2010,116(3):c159-c171. [8] 曾国华. 泌尿系结石诊疗进展与热点问题[J].中华泌尿外科杂志,2018,39(S1):1-4. [9] 叶子兴,乔逸,张实生,等.泌尿系结石代谢评估数据库的建立及临床初步应用[J].中华医学杂志,2020,100(26):2036-2039. [10] 王坤,李鸣,徐刚,等.新疆地区泌尿系结石成分分析及相关危险因素研究[J].临床泌尿外科杂志,2019,34(8):625-628. [11] 苏晓伟,王大明,丁德茂,等.感染性结石的相关临床易感因素研究[J].临床泌尿外科杂志,2021,36(4):284-287. [12] 李瑞宝,李碧君,林伟明,等.湛江地区肾结石成分特点及危险因素分析[J].中国民间疗法,2022,30(21):85-87. [13] 李本根,王洪涛,刘权,等.遵义地区单中心尿路结石成分分析[J].遵义医科大学学报,2024,47(8):806-814. [14] 郑府,姚娜娜,兰勇,等.以结石成分分析为基础的个体化指导方案在结石术后患者中的应用价值研究[J].国际泌尿系统杂志,2020,40(2):224-228.