Abstract：【Objective】 To investigate the clinical application effect of endoscopic retrograde cholangiopancreatography (ERCP) without nasobiliary drainage in the treatment of common bile duct stones. 【Methods】 The clinical data of 94 patients with common bile duct stones who underwent ERCP in our hospital from January 2021 to December 2023 were retrospectively analyzed. According to whether nasobiliary drainage was placed or not, the patients were divided into the observation group (without nasobiliary drainage, n=50) and the control group (with nasobiliary drainage, n=44). The perioperative indicators, incidence of complications, residual stone rate and recurrence rate were compared between the two groups. The serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBIL) before and after surgery, as well as the serum amylase (AMY) level 3 hours before and after surgery were compared between the two groups. 【Results】 The operation time, total hospitalization time and postoperative hospitalization time in the observation group were shorter than those in the control group, with statistically significant differences (P<0.05). There were no statistically significant differences in the intraoperative blood loss and Numerical Rating Scale (NRS) scores between the two groups (P>0.05). After surgery, the serum levels of ALT, AST and TBIL in both groups were lower than those before surgery, with statistically significant differences (P<0.05). There were no statistically significant differences in the serum levels of AMY, ALT, AST and TBIL between the two groups (P>0.05). There were no statistically significant differences in the incidences of postoperative abdominal infection or cholangitis, pancreatitis, gastrointestinal bleeding, hyperamylasemia and intestinal perforation between the two groups (P>0.05). There were no statistically significant differences in the postoperative residual bile duct stones and stone recurrence within half a year after surgery between the two groups (χ2=0.013, 0.033, all P>0.05). 【Conclusion】 ERCP has a good clinical effect in the treatment of common bile duct stones. On the premise of mastering the indications, the treatment scheme without nasobiliary drainage is safe and feasible.
贺炬, 黄鑫, 邱雪姣. 内镜逆行胰胆管造影免放置鼻胆管方案治疗胆总管结石的临床效果[J]. 医学临床研究, 2025, 42(12): 2042-2045.
HE Ju, HUANG Xin, QIU Xuejiao. Clinical Application Effect of Endoscopic Retrograde Cholangiopancreatography without Nasobiliary Drainage in the Treatment of Common Bile Duct Stones. JOURNAL OF CLINICAL RESEARCH, 2025, 42(12): 2042-2045.
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2025, Vol. 42 
