Efficacy of Huangqi Guizhi Wuwu Decoction Combined with Indirect Moxibustion and its Effect on T Lymphocyte Function in Treatment of Patients with Non-Small Cell Lung Cancer in Patients
GU Aili, ZHAO Ling, TANG Zhimin, et al
Department of Integrated Traditional Chinese and Western Medicine, Oncology, Zhengzhou Sixth People's Hospital, Zhengzhou Henan 450000
Abstract：【Objective】To investigate the efficacy of Huangqi Guizhi Wuwu Decoction combined with indirect moxibustion and its impact on T lymphocyte function in the treatment of patients non-small cell lung cancer (NSCLC).【Methods】A total of 106 patients with NSCLC were randomly divided into the control group and the observation group, with 53 patients in each group. The control group received conventional treatment, while the observation group was treated with Huangqi Guizhi Wuwu Decoction combined with indirect moxibustion on top of the conventional treatment. The efficacy, T lymphocyte function before and after treatment, traditional Chinese medicine syndrome scores, KPS scores, vascular endothelial growth factor (VEGF) levels, and the incidence of adverse reactions were compared between the two groups.【Results】 After treatment, the total effective rate in the observation group was higher than that in the control group (P<0.05). The observation group had significantly higher levels of CD3+, CD4+, and CD4+/CD8+ ratios, and lower CD8+ level compared to the control group (P<0.05). The TCM syndrome scores and VEGF level in the observation group were lower than those in the control group, while the KPS score in the observation group was higher than that in the control group (P<0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).【Conclusion】Huangqi Guizhi Wuwu Decoction combined with indirect moxibustion significantly improves the efficacy of treatment and T lymphocyte function in NSCLC patients, alleviates traditional Chinese medicine syndrome scores, enhances KPS score, reduces VEGF level, and lowers the incidence of adverse reactions.
顾爱丽, 赵玲, 唐志敏, 张鹏. 黄芪桂枝五物汤联合隔物灸治疗非小细胞肺癌的疗效及对患者T淋巴细胞功能的影响[J]. 医学临床研究, 2025, 42(4): 663-665.
GU Aili, ZHAO Ling, TANG Zhimin, et al. Efficacy of Huangqi Guizhi Wuwu Decoction Combined with Indirect Moxibustion and its Effect on T Lymphocyte Function in Treatment of Patients with Non-Small Cell Lung Cancer in Patients. JOURNAL OF CLINICAL RESEARCH, 2025, 42(4): 663-665.
2025, Vol. 42 
