Abstract：【Objective】To investigate the correlation between T-wave changes in lead aVL on electrocardiogram (ECG) and the degree of coronary artery stenosis in patients with stable angina pectoris. 【Methods】 The clinical data of 90 patients with stable angina pectoris admitted to our hospital from May 2018 to May 2021 were retrospectively analyzed. Based on prognosis, the patients were divided into a good prognosis group (n=60) and a poor prognosis group (n=30). General data and serum markers [cardiac troponin I (cTnI), high-sensitivity C-reactive protein (hs-CRP), brain natriuretic peptide (BNP), and creatine kinase-MB (CK-MB)] were compared between the two groups. The degree of coronary artery stenosis was compared among patients with different T-wave changes in lead aVL. Multivariate logistic regression analysis was used to identify independent risk factors for poor prognosis. 【Results】The proportions of T-wave changes in lead aVL, ST-segment elevation, pathological Q waves, and coronary artery stenosis were significantly higher in the poor prognosis group than in the good prognosis group (P<0.05). Logistic regression analysis showed that T-wave changes in lead aVL, ST-segment elevation, pathological Q waves, and coronary artery stenosis were all risk factors for poor prognosis in patients with stable angina pectoris (P<0.05). Based on T-wave changes in lead aVL, patients were further divided into a T-wave change group and a no T-wave change group. The degree of mid-segment stenosis in the left anterior descending artery was significantly higher in the T-wave change group than in the no T-wave change group (P<0.05).【Conclusion】 T-wave changes in lead aVL, ST-segment elevation, pathological Q waves, and coronary artery stenosis are risk factors for poor prognosis in patients with stable angina pectoris. Moreover, T-wave changes in lead aVL can predict the degree of mid-segment stenosis in the left anterior descending artery.
翟海杰. 稳定型心绞痛患者心电图aVL导联T波改变与冠状动脉狭窄程度的相关性[J]. 医学临床研究, 2025, 42(4): 656-658.
ZHAI Haijie. Correlation between T-Wave Changes in Lead aVL on Electrocardiogram and Degree of Coronary Artery Stenosis in Patients with Stable Angina Pectoris. JOURNAL OF CLINICAL RESEARCH, 2025, 42(4): 656-658.
[1] 徐卫刚, 彭德荣, 陈晨,等. 社区冠心病患者自我管理现状及影响因素研究[J].中国全科医学, 2019, 22(28):3516-3522. [2] 杨帆,袁海军.CT冠状动脉造影血流储备分数在心脏病变中的诊断价值[J].医学临床研究,2022,39(12):1792-1795. [3] 廖芯, 刘春燕, 张辰,等. SAAHECG对冠心病的诊断价值及与冠状动脉狭窄程度的关系探讨[J].重庆医学, 2022,51(10):1719-1730. [4] 卫旭瑛, 李传资, 唐文才,等. 多层螺旋CT与动态心电图对老年糖尿病患者冠状动脉病变诊断的比较[J].中国老年学杂志, 2021,41(9):1818-1821. [5] 中华医学会心血管病学分会,中华心血管病杂志编辑委员会.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206. [6] ZHU J, WU S L, HU S G, et al. NLRP3 inflammasome expression in peripheral blood monocytes of coronary heart disease patients and its modulation by rosuvastatin[J].Mol Med Rep,2019,20(2):1826-1836. [7] OPOLSKI M P, GRANSAR H, LU Y, et al. Prognostic value of chronic total occlusions detected on coronary computed tomographic angiography[J].Heart,2019,105(3):196-203. [8] TOMOYUKI K , SATOSHI H , KAZUOMI K . Notched P-Wave on Digital Electrocardiogram Predicts Cardiovascular Events in Patients with Cardiovascular Risks: The Japan Morning Surge Home Blood Pressure Study[J].Cardiology,2022,147(3):307-314. [9] 金海霞, 鲍俊成, 喻涛,等. aVL导联T波改变在预测急性冠状动脉综合征预后中的价值[J].中国动脉硬化杂志, 2019, 27(12):1058-1061. [10] 蒋萍, 宋莹, 姜琳,等. 稳定性冠心病患者ABO血型与经皮冠状动脉介入治疗远期预后的相关性[J].中华医学杂志, 2019, 99(29):2288-2292. [11] 单红英, 杨学东, 徐勇,等. 急性前壁ST段抬高型心肌梗死患者经皮冠状动脉介入治疗后病理性Q波消失对临床预后的影响[J].中国急救医学, 2021,41(8):718-724. [12] 肖美娟, 杨丽, 付宇,等. 稳定型与变异型心绞痛患者心电图及冠状动脉造影特点分析[J].中国现代医学杂志, 2021, 31(10):74-78. [13] 张诗梦, 张恒莉, 崔畅,等. 完全性左束支传导阻滞患者aVL导联q波与器质性心脏病相关性的探讨[J].南京医科大学学报:自然科学版, 2020, 40(4):557-562. [14] 吕常智, 杨闯, 徐万林. 急性冠脉综合征患者aVL导联T波倒置对左前降支中段狭窄的预测价值[J].中华老年心脑血管病杂志, 2022,24(1):43-46. [15] JING N, SHUAI M, YA L T, et al. Guiding extension catheter facilitated percutaneous coronary intervention for a dextrocardia patient with acute left anterior descending artery occlusion: a case report[J].J Geriatr Cardiol,2020, 17(12):60-62.
2025, Vol. 42 
