Abstract：【Objective】To explore the therapeutic effect of group painting therapy combined with clozapine in the treatment of chronic schizophrenia. 【Methods】A total of 100 patients with chronic schizophrenia who were hospitalized in our hospital from February 2019 to February 2023 were selected as the study subjects. They were randomly divided into the observation group and the control group using a random number table method, with 50 cases in each group. The control group received treatment with clozapine, while the observation group received a combination of group painting therapy on the basis of the control group. We compared the clinical efficacy of two groups and evaluated their positive and negative symptom scale (PANSS), quality of life scale for schizophrenia patients (SQLS), and social function assessment scale for hospitalized psychiatric patients (SSPI). We also compared the incidence of adverse reactions between the two groups. 【Results】The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the positive factor score, negative factor score, general psychopathological score, and total score of the two groups were significantly lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05); The scores and total scores of psychosocial, energy and motivation, symptoms and side effects in the two groups of patients were lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05); The daily life function, motility and social interaction, social activity skill scores, and total scores of the two groups were lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients (P>0.05).【Conclusion】The combination of group painting therapy and clozapine has significant clinical efficacy in the treatment of chronic schizophrenia, which can effectively improve the positive and negative symptoms of patients, as well as improve their quality of life and social function, with high safety.
张春良. 团体绘画疗法与氯氮平联合治疗慢性精神分裂症患者的疗效[J]. 医学临床研究, 2024, 41(12): 1867-1869.
ZHANG Chunliang. Observation on the Therapeutic Effect of Group Painting Therapy Combined with Clozapine in the Treatment of Chronic Schizophrenia. JOURNAL OF CLINICAL RESEARCH, 2024, 41(12): 1867-1869.
2024, Vol. 41 
