Abstract：【Objective】To explore the clinical effect of hysterolaparoscopy combined with medication for ovulation induction in the treatment of patients with tubal infertility. 【Methods】 Sixty patients with tubal infertility treated in our hospital were selected as the study subjects. They were randomly divided into Group A(treated with hysterolaparoscopy combined with Urofollitrophin), Group B(treated with hysterolaparoscopy combined with letrozole), and Group C(treated with hysteroscopy) using a random number table method, with 20 cases in each group. Two groups of patients were compared in terms of ovarian function indicators, postoperative pregnancy time, pregnancy rate, miscarriage rate, delivery rate, and abnormal fetal rate.【Results】 After treatment, the levels of ovarian function indicators such as estradiol(E2), follicle stimulating hormone(FSH), and luteinizing hormone(LH) in groups A, B, and C were higher than before treatment(P<0.05); After treatment, the levels of LH, FSH, and E2 in Group A were significantly higher than those in Group B and Group C(P<0.05); After treatment, the levels of LH, FSH, and E2 in Group B were significantly higher than those in Group C(P<0.05). The pregnancy rates of Group A, Group B, and Group C were 85.00%, 75.00%, and 55.00%, respectively. The differences among the three groups were statistically significant(P<0.05). The postoperative conception time in Group A was shorter than that in Group B and Group C(P<0.05); The postoperative conception time in Group B was shorter than that in Group C(P<0.05). The abortion rates of Group A, Group B, and Group C were 5.88%, 6.67%, and 27.27%, respectively. The difference among the three groups was statistically significant(P<0.05); The delivery rates of Group A, Group B, and Group C were 94.12%, 93.33%, and 72.73%, respectively. The differences among the three groups were statistically significant(P<0.05); The rates of abnormal fetuses in Group A, Group B, and Group C were 0, 0, and 9.09%, respectively. There was no statistically significant difference among the three groups(P>0.05).【Conclusion】 The combination of Hysterolaparoscopy and medication for ovulation induction can effectively improve ovarian function, increase pregnancy and delivery rates, and reduce miscarriage rates in patients with tubal infertility. However, compared to letrozole treatment, the combination of hysteroscopy and urinary follicle stimulating hormone treatment is more effective and worthy of clinical promotion and application.
孙海云, 赵通, 胡玉宏, 孟缓缓, 唐琳, 毛宝红. 宫腹腔镜联合药物促排卵治疗输卵管性不孕患者的临床效果*[J]. 医学临床研究, 2024, 41(6): 817-819.
SUN Haiyun, ZHAO Tong, HU Yuhong,et al. Clinical Efficacy of Hysterolaparoscopy Combined with Medication for Ovulation Induction in the Treatment of Tubal Infertility Patients. JOURNAL OF CLINICAL RESEARCH, 2024, 41(6): 817-819.
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2024, Vol. 41 
