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医学临床研究  2023, Vol. 40 Issue (11): 1645-1648    DOI: 10.3969/j.issn.1671-7171.2023.11.009
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盐酸托莫西汀联合听觉统合训练治疗儿童注意缺陷多动障碍的效果
牟春燕, 韩波*
宝鸡市妇幼保健院,陕西 宝鸡 721000
The Effect of Atomoxetine Hydrochloride Combined with Auditory Integration Training in the Treatment of Attention Deficit Hyperactivity Disorder in Children
MOU Chunyan, HAN Bo
Baoji Maternal and Child Health Hospital,Baoji Shaanxi 721000
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摘要 【目的】探讨盐酸托莫西汀联合听觉统合训练(AIT)治疗儿童注意缺陷多动障碍(ADHD)的疗效。【方法】选取2021年4月至2022年8月本院收治的210例ADHD患儿,根据随机数字表法将其分为对照组和观察组,每组105例。对照组采用盐酸托莫西汀治疗,观察组在对照组的基础上联合AIT治疗,比较两组患儿反应时间、错误数、漏报数,中文版ADHD评定量表父母版(ADHDRS-Ⅳ-P)评分,联合型瑞文测验(CRT)评分,临床疗效及不良反应。【结果】治疗后,两组患儿反应时间、错误数、漏报数均低于治疗前(P<0.05),且观察组低于对照组(P<0.05);两组患儿注意力不集中、多动/冲动、对立违抗评分和总评分均低于治疗前(P<0.05),且观察组低于对照组(P<0.05)。观察组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组患儿比较推理能力、类同比较能力、知觉辨别能力、系列关系能力、抽象推理能力、智商数评分均高于治疗前(P<0.05),且观察组高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。【结论】盐酸托莫西汀联合AIT治疗儿童ADHD临床疗效较好,可提高认知能力,安全可靠。
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牟春燕
韩波
关键词 注意力缺陷障碍伴多动盐酸托莫西汀/治疗应用听觉/生理学    
Abstract:【Objective】To explore the efficacy of atomoxetine hydrochloride combined with auditory integration training(AIT) in the treatment of attention deficit hyperactivity disorder(ADHD) in children.【Methods】 A total of 210 children with ADHD admitted to our hospital from April 2021 to August 2022 were selected and randomly divided into a control group and an observation group according to a random number table method,with 105 cases in each group.The control group was treated with atomoxetine hydrochloride,while the observation group was treated with atomoxetine hydrochloride combined with AIT. The response time,error number,and missed report number of the two groups were compared,as well as the scores of the Chinese version of ADHD rating scale-parent version(ADHDRS-Ⅳ-P),combined raven's test(CRT),clinical efficacy,and adverse reactions. 【Results】After treatment,the response time,error number,and missed report number of the two groups were lower than those before treatment(P<0.05),and the observation group was lower than the control group(P<0.05). The attention deficit,hyperactivity/impulsivity,oppositional defiance,and total scores of the two groups were lower than those before treatment(P<0.05),and the observation group was lower than the control group(P<0.05). The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05). After treatment,the scores of reasoning ability,similarity comparison ability,perceptual discrimination ability,serial relationship ability,abstract reasoning ability,and IQ number of the two groups were higher than those before treatment(P<0.05),and the observation group was higher than the control group(P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).【Conclusion】 Atomoxetine hydrochloride combined with AIT has better clinical efficacy in the treatment of ADHD in children,as well as enhance their cognitive ability,and is safe and reliable.
Key wordsAttention Deficit Disorder with Hyperactivity    Atomoxetine Hydrochloride/TU    Auditory Perception/PH
收稿日期: 2023-05-31     
中图分类号:  R725  
通讯作者: * E-mail:hanbonihao@163.com   
引用本文:   
牟春燕, 韩波. 盐酸托莫西汀联合听觉统合训练治疗儿童注意缺陷多动障碍的效果[J]. 医学临床研究, 2023, 40(11): 1645-1648.
MOU Chunyan, HAN Bo. The Effect of Atomoxetine Hydrochloride Combined with Auditory Integration Training in the Treatment of Attention Deficit Hyperactivity Disorder in Children. JOURNAL OF CLINICAL RESEARCH, 2023, 40(11): 1645-1648.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2023.11.009     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2023/V40/I11/1645
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