Abstract:【Objective】To analyze the sonographic findings of fetal biliary dilatation to predict clinical prognosis.【Methods】We retrospectively studied the prenatal ultrasound screening of fetal biliary dilation (BD) from March 2018 to August 2020 in our hospital. The ultrasonic characteristics of BD and changes of cystic mass before and after birth were analyzed to track the prognosis.【Results】Pregnant women were 19 to 35 (27.7±4.2) years old and the average gestational age for prenatal cystic mass to be discovered at the first time was 18.1 to 33.6 (25.2±3.4) weeks. There were 22 fetal BD cases diagnosed prenatally, including 17 female fetuses (77.3%) and 5 male fetuses (22.7%). The coincidence rate of postpartum ultrasound was 81.8% (18/22) and the misdiagnosis rate was 18.2% (4/22), including 1 case of cystic biliary atresia, 2 cases of liver cyst, and 1 case of cyst regression. Cystic masses were mostly located in the first hepatic hilar area and the periphery of the gallbladder. There were 3 cases of gallbladder ultrasound imaging without obvious filling in the gallbladder area; while the other 19 cases had normal gallbladder morphology. There were 13 cases of cystic masses showing irregular shape and 9 cases were regular in shape. All the cases showed clear boundaries. There were 2 cases with floating bright spots in the mass, and the rest showed normal ultrasound internally. In the 22 cases, only 1 case of intrahepatic bile duct dilation was seen and 21 cases of cystic mass were linked to intrahepatic bile duct are visible. Except for the 4 misdiagnosed cases, the cystic masses in the remaining cases increased with the prolonged gestational age.【Conclusions】Prenatal ultrasound screening is a good way to make diagnosis for fetal bile duct dilatation, which can improve the prognosis.
[1] Ronnekleiv-Kelly SM,Soares KC,Ejaz A,et al.Management of choledochal cysts[J].Curr Opin Gastroenterol,2016,32(3):225-231.
[2] Machado NO,Chopra PJ,Ullal AJ,et al.Choledochal cyst in adults:etiopathogenesis,presentation,managenent,and out-come-case series and review[J].Gastroenterol Res Pract,2015,2015(5):602591.
[3] 中华医学会外科学分会胆道外科学组.胆管扩张症诊断与治疗指南(2017版)[J].中华消化外科杂志,2017,16(8): 767-774.
[4] 何苗,谢红宁,杜柳,等.莱尔肝门部囊性占位的超声表现及临床预后研究[J].中华超声影像学杂志,2019,28(7): 621-624.
[5] Khalil A, Cooke PC, Mantovani E, et al. Outcome of first trimester fetal abdominal cysts: cohort study and review of the literature[J].Ultrasound Obstet Gynecol,2014,43(4):413-419.
[6] 肖静,杨洋,向义.先天性胆总管囊肿的特点及危险因素[J].中华围产医学杂志,2020,23(1):8-17.
[7] 胡东来,郭晓东,孙志南,等.胎儿先天性胆总管囊肿的产前诊断及生后结局[J].中华围产医学杂志,2017,20(6):407-413.
[8] 田蓉,彭清海,袁红霞,等.先天性小肠闭锁或狭窄的产前超声诊断分析[J].医学临床研究,2020,37(7):1026-1028.
[9] 崔晏春,王晓曼,贾立群.新生儿及小婴儿肝门区囊肿性病变的超声鉴别诊断[J].中国小儿急救医学,2019,26(9):600-603.
[10] 李颀,李龙.产前诊断胆道闭锁影像学研究[J].临床小儿外科志,2014,13(2):129-132.
[11] 肖静,乐盛麟,李鹏,等.胎儿先天性胆总管囊肿的产前诊断及生后结局[J].中华围产医学杂志,2017,20(6):407-413.