Abstract：【Objective】To explore the clinical effect of intermittent occlusion combined with visual perceptual learning on amblyopia in children.【Methods】Eighty cases of amblyopia in our hospital from January 2016 to January 2018 were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with intermittent occlusion, and the observation group was treated with visual perception learning on the basis of the control group. The visual improvement of the two groups before treatment and after 3 months, 6 months, 12 months were compared.【Results】The basic cure rate of the observation group was better than that of the control group, the difference was statistically significant (P<0.05); there was no statistically significant difference in BCVA between the two groups before and 3 months after treatment (P>0.05), and the BCVA of the observation group was better than that of the control group at 6 and 12 months after treatment, the difference was statistically significant (P<0.05); the best corrected visual acuity of the observation group increased by (1.00±0.40) lines on average during 3-6 months of treatment, which was better than that of the control group (0.70±0.30). The difference was statistically significant (P<0.05); after treatment, the stereopsis of both groups was improved. The proportion of people whose stereopsis recovery≤60″ in the observation group was better than that in the control group, and the difference between the two groups was statistically significant (P<0.05).【Conclusion】Intermittent occlusion combined with visual perceptual learning can improve the corrected visual acuity of children with amblyopia and improve the cure rate. It is worthy of clinical application.
[1] 中华医学会眼科学分会斜视与小儿眼科学组.弱视诊断专家共识(2011年)[J].中华眼科杂志,2011,47(8):768. [2] Tian C, Peng X, Fan Z, et al. Corneal refractive surgery and phakic intraocular lens for treatment of amblyopia caused by high myopia or anisometropia in children[J].Chin Med J (Engl),2014, 127(11): 2167-2172. [3] 程子昂,谢祥勇.弱视治疗进展[J].国际眼科杂志,2018,18(8):1427-1430. [4] 邓显峰,朱峰,陈伟, 等.阿托品压抑疗法和遮盖疗法在治疗小儿弱视中的效果观察[J].现代生物医学进展,2015,15(22):4345-4347. [5] 沈学成.间断遮盖治疗对弱视患儿的临床疗效分析[J].中国妇幼保健,2016,31(12):2496-2498. [6] 孟艳菊,张姝贤,南莉.单纯屈光参差弱视儿童连续全遮盖治疗3个月对视功能的影响分析[J].中国妇幼保健,2015,30(14):2182-2184. [7] Wallace DK, Pediatric Eye Disease Investigator Group. A randomized trial to evaluate 2 hours of daily patching for strabismic and anisometropic amblyopia in children[J].Ophthalmology,2006, 113(6): 904-912. [8] 刘秀丽,宋玉伟.弱视的视觉系统损害与功能障碍[J].四川医学,2015,36(2):241-242. [9] 张敏,魏小平,李芳.多媒体眼功能锻炼与间断遮盖治疗对儿童弱视治疗效果的比较[J].中国妇幼保健,2014,29(33):5523-5525. [10] 田璐,南莉,丁肇凤, 等.传统弱视治疗方法联合视功能训练治疗远视性屈光参差性弱视的疗效[J].眼科新进展,2018,38(10):955-958. [11] Bavelier D, Levi DM, Li RW, et al. Removing brakes on adult brain plasticity: from molecular to behavioral interventions[J].J Neurosci,2010, 30(45): 14964-14971.
2020, Vol. 37 
