Abstract：Objective To compare the clinical efficacy and safety of laparoscopic and open surgery in the treatment of appendicitis in pregnancy. Methods A retrospective analysis was made of 56 cases of appendicitis complicating pregnancy treated in our hospital from January 2014 to January 2017. According to the surgical methods, 32 cases were divided into laparoscopic surgery (minimally invasive group) and 24 cases were treated by open surgery (control group). The operation time, blood loss, hospitalization time, hospitalization expenses, surgical complications, serum C-reactive protein (CRP), tumor necrosis factor-α(TNF-α), white blood cell (WBC) levels and pregnancy outcomes were compared between the two groups. Results The bleeding volume and hospitalization time in the minimally invasive group were significantly less than those in the control group, and the hospitalization expenses were significantly higher than those in the control group, with statistical significance (P<0.05), but there was no significant difference in the operation time between the two groups (P>0.05); there was no significant difference in the levels of serum CRP, TNF-αand WBC in the peripheral blood between the two groups before operation (P>0.05). The levels of CRP, TNF-αand WBC in peripheral blood in minimally invasive group were significantly lower than those in control group at D1 and D3 after operation (P<0.05). The complication rate in minimally invasive group was 6.25%, significantly lower than that in control group (29.17%,P<0.05). There was no significant difference in gestational weeks, birth weight, 1 minute and 5 minute Apgar scores between the two groups during follow-up until the end of delivery (P>0.05).Conclusion Laparoscopic minimally invasive surgery in the treatment of appendicitis during pregnancy has obvious curative effect and high safety, which is worthy of clinical application.
李腾芳, 李全, 辜军. 腹腔镜和开腹手术治疗妊娠期阑尾炎的疗效及安全性比较[J]. 医学临床研究, 2019, 36(2): 297-299.
LI Teng-fang, LI Quan, Gu Jun. Clinical Efficacy and Safety of Laparoscopic and Open Surgery for Appendicitis in Pregnancy. JOURNAL OF CLINICAL RESEARCH, 2019, 36(2): 297-299.
2019, Vol. 36 
