Abstract:【Objective】 To investigate the curative effect of traditional Chinese medicine retention enema in the treatment of patients with recurrence of polyps after colon polypectomy. 【Methods】 A total of 86 patients with colonic polyp recurrence who were admitted to our hospital from April 2020 to April 2025 were selected as the research objects. According to the random number table method, they were divided into the control group of 43 cases with 5-fluorouracil enema and the observation group of 43 cases with traditional Chinese medicine enema. The clinical efficacy, polyp mucosal damage score, polyp number, polyp diameter and adverse reactions were compared between the two groups. 【Results】 The total effective rate of the traditional Chinese medicine prescription group was 90.70%(39/43), which was higher than that of the control group (67.44%, 29/43). The difference was statistically significant (P<0.05). Before treatment, there were no significant differences in the score of polyp mucosal damage, the number of polyps, and the diameter of polyps between the two groups (P>0.05). After treatment, the scores for the degree of mucosal injury, the number of polyps, and the polyp diameter in both groups were lower than their respective pre-treatment levels; furthermore, the values in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05).During the treatment period, no adverse reactions such as rashes, vomiting, nausea, or impairment of liver and kidney function were observed in either group; the difference was not statistically significant (P>0.05). 【Conclusion】 Traditional Chinese medicine retention enema demonstrates favorable clinical efficacy in the treatment of patients with recurrent colon polyps after colon polypectomy. It can significantly reduce the diameter of polyps, improve mucosal damage, and reduce the recurrence rate, which is worthy of clinical promotion.
宋鹏举, 王尚园. 中药保留灌肠治疗结肠息肉切除术后复发患者的临床疗效[J]. 医学临床研究, 2026, 43(3): 422-424.
SONG Pengju, WANG Shangyuan. Clinical Efficacy of Traditional Chinese Medicine Retention Enema in Patients with Recurrence after Colon Polyp Resection. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 422-424.