Efficacy of Two Different Approaches of Hip Arthroplasty in the Treatment of Patients with Ankylosing Spondylitis Complicated by Hip Joint Lesions and their Impact on Serum Inflammatory Factor Levels
HUANG Fei
Department of Orthopedics, Xiangcheng Oriental Hospital, Zhoukou Henan 466200
Abstract：【Objective】To explore the efficacy of two different approaches of hip arthroplasty in the treatment of patients with ankylosing spondylitis (AS) complicated by hip joint lesions and their impact on serum inflammatory factor levels. 【Methods】A total of 86 patients with AS complicated by hip joint lesions who underwent hip arthroplasty in our hospital from January 2020 to January 2024 were selected. According to the different surgical approaches, they were divided into the observation group (anterior approach) and the control group (posterolateral approach), with 43 cases in each group. The Visual Analogue Scale (VAS) score, hip function score [Harris Hip Score (HHS) system], Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, serum inflammatory factor [interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)] levels, and hip abduction and flexion angles were compared between the two groups before and after treatment. 【Results】After treatment, the WOMAC score and VAS score of the observation group were lower than those of the control group (P<0.05). After treatment, the levels of inflammatory factors in the observation group were lower than those in the control group, and the HHS score was higher than that in the control group (P<0.05). At 1 month and 3 months after treatment, the hip abduction angle and hip flexion angle of the observation group were larger than those of the control group, and the differences were statistically significant (P<0.05). 【Conclusion】Compared with posterolateral approach hip arthroplasty, anterior approach hip arthroplasty has a more significant effect on improving hip function, reducing pain scores and lowering serum inflammatory factor levels in patients with AS complicated by hip joint lesions.
黄飞. 两种不同入路髋关节置换术治疗强直性脊柱炎合并髋关节病变患者的疗效及对血清炎症因子水平的影响[J]. 医学临床研究, 2025, 42(8): 1398-1401.
HUANG Fei. Efficacy of Two Different Approaches of Hip Arthroplasty in the Treatment of Patients with Ankylosing Spondylitis Complicated by Hip Joint Lesions and their Impact on Serum Inflammatory Factor Levels. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1398-1401.
2025, Vol. 42 
