Abstract：【Objective】To explore the clinical value of simplified contrast-enhanced CT in the differential diagnosis of adrenal adenoma and adrenal pheochromocytoma. 【Methods】The clinical data of 60 patients with pathologically confirmed adrenal tumors admitted to our hospital from August 2021 to December 2024 were analyzed retrospectively. The patients were divided into the adrenal adenoma group and the adrenal pheochromocytoma group according to different tumor types, with 30 cases in each group. The CT imaging features and CT density parameters of the two groups were compared, and the receiver operating characteristic (ROC) curve was used to analyze the value of simplified contrast-enhanced CT in the differential diagnosis of the two types of tumors. 【Results】 There were statistically significant differences in the shape and cystic degeneration between the two groups (P<0.05); there was no statistically significant difference in calcification (P>0.05). The plain CT value, portal venous phase CT value, absolute enhancement value, relative enhancement ratio, long diameter of the lesion, and short diameter of the lesion in the adrenal pheochromocytoma group were all higher than those in the adrenal adenoma group, with statistically significant differences (P<0.05). ROC curve analysis showed that the long diameter of the lesion had the best diagnostic efficiency [area under the curve (AUC)=0.913], with a sensitivity of 86.7% and a specificity of 83.3% when the cut-off value was 33.805 mm; the sensitivity was the highest (93.3%) when the portal venous phase CT value was 102.15 HU, and the specificity was the highest(93.3%) when the plain CT value was 28.38 HU. 【Conclusion】Simplified contrast-enhanced CT has important clinical application value in the differential diagnosis of adrenal adenoma and adrenal pheochromocytoma, and the combination of the long diameter of the lesion and the portal venous phase CT value can be used as a reliable indicator for differentiating adrenal adenoma and pheochromocytoma.
宋乐乐, 陈顺军, 张亚斌. 简化增强CT在肾上腺腺瘤与肾上腺嗜铬细胞瘤鉴别诊断中的应用价值[J]. 医学临床研究, 2025, 42(10): 1749-1752.
SONG Lele, CHEN Shunjun, ZHANG Yabin. Clinical Value of Simplified Contrast-Enhanced CT in the Differential Diagnosis of Adrenal Adenoma and Adrenal Pheochromocytoma. JOURNAL OF CLINICAL RESEARCH, 2025, 42(10): 1749-1752.
2025, Vol. 42 
