3D Bravo联合Cube Flair增强序列在微小脑转移瘤诊断中的临床应用价值<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2025.08.004

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摘要【目的】探讨3D Bravo联合Cube Flair增强序列在微小脑转移瘤诊断中的临床应用价值。【方法】选择2022年1月至2024年3月本院收治的75例脑转移的肿瘤患者,在 1.5T磁共振成像仪上完成颅脑增强FSE T₁WI、3D Bravo、Cube Flair扫描,分别统计三种增强序列及3D Bravo联合Cube Flair序列所检测出的微小脑转移瘤病灶的数目,根据连续2次及以上随访复查的结果来证实诊断结果。【结果】75例患者共发现微小脑转移瘤病灶420个,其中常规FSE T₁WI增强共发现279个转移瘤病灶,检出率66.4%;3D Bravo增强序列共发现339个转移瘤病灶,检出率80.7%;Cube Flair增强序列共发现377个转移瘤病灶,检出率89.8%;3D Bravo联合Cube Flair增强序列共发现402个转移瘤病灶,检出率95.7%。 FSE T₁WI、3D Bravo、Cube Flair三种增强序列以及3D Bravo联合Cube Flair增强序列对微小脑转移瘤病灶检出率比较,差异均有统计学意义(P<0.05)。Cube Flair序列在囊性脑转移瘤的随访诊断中存在假阳性的情况。【结论】3D Bravo联合Cube Flair增强序列能够显著提高微小脑转移瘤病灶的检出率,特别是在脑表浅区微小转移瘤的诊断中具有显著的临床应用价值,可以成为常规FSE T₁WI增强序列的替代序列。

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关键词 ：肿瘤转移, 脑肿瘤, 磁共振成像, 诊断

Abstract：【Objective】To explore the clinical application value of 3D Bravo combined with Cube Flair enhanced sequence in the diagnosis of small cerebral metastatic tumors. 【Methods】Seventy-five tumor patients with cerebral metastases admitted to our hospital from January 2022 to March 2024 were selected. Cranial enhanced FSE T₁WI, 3D Bravo, and Cube Flair scans were performed on a 1.5T magnetic resonance imaging scanner. The number of small cerebral metastatic tumor lesions detected by the three enhanced sequences and the 3D Bravo combined with Cube Flair sequence were counted respectively, and the diagnostic results were confirmed through two or more consecutive follow-up reviews. 【Results】A total of 420 small cerebral metastatic tumor lesions were found in 75 patients. Among them, 279 metastatic tumor lesions were found by conventional FSE T₁WI enhancement, with a detection rate of 66.4%; 339 metastatic tumor lesions were found by the 3D Bravo enhanced sequence, with a detection rate of 80.7%; 377 metastatic tumor lesions were found by the Cube Flair enhanced sequence, with a detection rate of 89.8%; and 402 metastatic tumor lesions were found by the 3D Bravo combined with Cube Flair enhanced sequence, with a detection rate of 95.7%. There were statistically significant differences in the detection rates of small cerebral metastatic tumor lesions among the FSE T₁WI, 3D Bravo, Cube Flair enhanced sequences and the 3D Bravo combined with Cube Flair enhanced sequence (P<0.05). The Cube Flair sequence had false-positive cases in the follow-up diagnosis of cystic cerebral metastatic tumors. 【Conclusion】The 3D Bravo combined with Cube Flair enhanced sequence can significantly improve the detection rate of small cerebral metastatic tumor lesions, especially in the diagnosis of small metastatic tumors in the superficial area of the brain, which has significant clinical application value and can be an alternative sequence to the conventional FSE T₁WI enhanced sequence.

Key words： Neoplasm Metastasis Brain Neoplasms Magnetic Resonance Imaging Diagnosis

收稿日期: 2025-01-16

中图分类号:

R739.41

基金资助:^*湖南省卫生健康委科研计划项目(编号202209013799)

通讯作者: ^**E-mail:silong0305@163.com

引用本文:

伍君子, 刘帆, 邱玲玲, 彭锋, 龚逢杰. 3D Bravo联合Cube Flair增强序列在微小脑转移瘤诊断中的临床应用价值^*[J]. 医学临床研究, 2025, 42(8): 1307-1310.
WU Junzi, LIU Fan, QIU Lingling, et al. Clinical Application Value of 3D Bravo Combined with Cube Flair Enhanced Sequence in the Diagnosis of Small Cerebral Metastatic Tumors. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1307-1310.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2025.08.004 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2025/V42/I8/1307

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