Abstract：【Objective】To investigate the effect of transurethral plasma enucleation of prostate in the treatment of benign prostatic hyperplasia (BPH) with prostate volume >80 mL. 【Methods】A total of 128 BPH patients with prostate volume >80 mL was analyzed retrospectively. They were divided into observation group (n=66) and control group (n=62). The control group was treated with transurethral bipolar resection of the prostate and the observation group was treated with transurethral plasma enucleation of the prostate. The operation conditions and surgical stress [serum interleukin (IL)-6 and C-reactive protein (CRP) before and 24 hours after operation], urodynamics [maximum urinary flow rate (Qmax), residual urine volume (RUV), maximum detrusor pressure (Pdet)] and complications before and 3 months after operation were compared between the two groups.【Results】The intraoperative blood loss, bladder flushing time and hospital stay in the observation group were less than those in the control group, and the quality of lesion resection was greater than that in the control group (P<0.05). 24 hours after operation, the levels of serum IL-6 and CRP in the two groups were higher than those before operation, and the levels in the observation group were lower than those in the control group (P<0.05). Three months after operation, the Qmax of the two groups was higher than that before operation, RUV and Pdet were lower than that before operation, and the difference between the observation group and the control group was statistically significant (P<0.05). The incidence of complications in the observation group was 3.03% (2/66), lower than 6.45% (4/62) in the control group, but the difference was not statistically significant(χ2=0.247,P=0.619). 【Conclusion】Transurethral plasma enucleation of the prostate is effective in the treatment of BPH with prostate volume >80 mL, it can reduce body stress, improve urodynamics, have less complications and high safety.
2022, Vol. 39 
