Abstract：【Objective】To explore the application effect of probiotics combined with Shuangzuotai effervescent tablets in the treatment of bacterial vaginitis (BV). 【Methods】A total of 106 patients with BV in our hospital from February 2019 to December 2020 were selected and divided into two groups by random number table method. The control group was treated with Shuangzuotai effervescent tablets alone, while the observation group accepted Shuangzuotai effervescent tablets combined with probiotics. The clinical efficacy, symptom relief time, changes in the vaginal environment, adverse reactions and recurrence rates were compared between the two groups. 【Results】After treatment, the total effective rate of the observation group reached 94.34%, which was significantly higher than 81.13% of the control group (P<0.05). Clinical symptoms' relief time such as vaginal pain, itching, abnormal leucorrhea, and mucosal congestion in the observation group were all shorter than those in the control group (P<0.05). After treatment, the percentage of clue cells >20%, the percentage of positive amine test and the percentage of vaginal secretion (pH>4.5) in the observation group were lower than those in the single group (P<0.05); The recurrence rate of the observation group was 3.77%, which was lower than that of the control group 15.09% (P<0.05). 【Conclusion】Application of probiotics combined with Shuangzuotai effervescent tablets is effective in the treatment of bacterial vaginitis. It also has a certain value in reducing the recurrence rate and alleviating clinical symptoms.
何静, 白瑞. 益生菌联合双唑泰泡腾片治疗细菌性阴道炎的疗效分析[J]. 医学临床研究, 2022, 39(2): 222-224.
HE Jing, BAI Rui. Effect of Probiotics Combined with Shuangzuotai Effervescent Tablets in the Treatment of Bacterial Vaginitis. JOURNAL OF CLINICAL RESEARCH, 2022, 39(2): 222-224.
2022, Vol. 39 
