基于中毒程度的分层干预策略对急诊留观急性酒精中毒患者预后的影响<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2026.04.009

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摘要 【目的】探讨基于中毒程度的分层干预策略对急诊留观急性酒精中毒患者预后的影响。【方法】回顾性分析2022年1月至2024年8月在本院急诊留观的240 例急性酒精中毒患者的临床资料,根据干预方法的不同将患者分为观察组(n=122)和对照组(n=118)。对照组采用急诊常规干预措施,观察组采用基于中毒程度实施分层干预策略。比较两组不良事件发生率、急诊留观时间及预后情况,采用多因素 Logistic 回归分析影响患者预后的相关因素。【结果】观察组与对照组患者中毒程度分布情况比较,差异无统计学意义(P>0.05)。观察组总不良事件发生率为24.59%(30/122),显著低于对照组的55.08%(65/118),差异有统计学意义(χ²=8.364,P=0.004)。观察组平均急诊留观时间显著短于对照组,差异有统计学意义(P<0.05)。不同中毒程度、干预方式、基础疾病、饮酒量、就诊时间患者的预后不良所占比例比较,差异均有统计学意义(P<0.05)。多因素 Logistic 回归分析结果显示,重度中毒、未实施分层干预、合并基础疾病是患者预后不良的独立危险因素(P<0.05)。【结论】基于中毒程度的分层干预策略可显著降低急诊留观急性酒精中毒患者不良事件发生率,缩短留观时间,中毒程度、干预方式、基础疾病是影响预后的关键因素,临床需针对性制定急诊干预方案。

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	丁小方
	郭艳艳

关键词 ：急性酒精中毒, 急诊处理, 护理, 预后

Abstract：【Objective】 To investigate the prognostic impact of stratified intervention strategies based on intoxication severity in patients with acute alcohol poisoning under observation in the emergency department. 【Methods】 Clinical data of 240 patients with acute alcohol poisoning who received emergency observation in our hospital from January 2022 to August 2024 were retrospectively analyzed. The patients were divided into an observation group (n=122) and a control group (n=118) according to different intervention methods. The control group received routine emergency interventions, while the observation group received stratified interventions based on intoxication severity. The incidence of adverse events, emergency observation duration, and prognosis were compared between the two groups. Multivariate Logistic regression analysis was performed to identify factors associated with patient prognosis. 【Results】 There was no statistically significant difference in the distribution of intoxication severity between the observation group and the control group (P>0.05). The total incidence of adverse events in the observation group was 24.59% (30/122), which was significantly lower than 55.08% (65/118) in the control group, with a statistically significant difference (χ²=8.364, P=0.004). The mean emergency observation duration in the observation group was significantly shorter than that in the control group (P<0.05). Statistically significant differences were found in the proportion of poor prognosis among patients with different intoxication severity, intervention methods, underlying diseases, alcohol consumption, and time to hospital presentation (P<0.05). Multivariate Logistic regression analysis showed that severe intoxication, absence of stratified intervention, and comorbid underlying diseases were independent risk factors for poor prognosis (P<0.05). 【Conclusion】 Conclusion Stratified intervention strategies based on intoxication severity can significantly reduce the incidence of adverse events and shorten the observation duration in patients with acute alcohol poisoning under emergency observation. Intoxication severity, intervention modality, and underlying diseases are key prognostic factors, and targeted emergency intervention protocols should be formulated clinically.

Key words： Alcoholic Intoxication Emergency Treatment Nursing Care Prognosis

收稿日期: 2025-10-22

中图分类号:

R595.6

基金资助:^*2023年度常德市科技创新指导性项目(2023ZD107)

引用本文:

丁小方, 郭艳艳. 基于中毒程度的分层干预策略对急诊留观急性酒精中毒患者预后的影响^*[J]. 医学临床研究, 2026, 43(4): 559-562.
DING Xiaofang, GUO Yanyan. Prognostic Impact of Stratified Intervention Strategies Based on Intoxication Severity in Patients with Acute Alcohol Poisoning under Observation in the Emergency Department. JOURNAL OF CLINICAL RESEARCH, 2026, 43(4): 559-562.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2026.04.009 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2026/V43/I4/559

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