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| Clinical Efficacy of Shensong Yangxin Capsule Combined with Telmisartan Tablets and Metoprolol Tartrate Tablets in the Treatment of Hypertensive Patients Complicated with Arrhythmia |
| FAN Lili |
| Department of Pharmacy, the 83rd Group Military Hospital of the People's Liberation Army of China, Xinxiang Henan 453000 |
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Abstract 【Objective】 To explore the clinical efficacy of Shensong Yangxin Capsule combined with telmisartan tablets and metoprolol tartrate tablets in the treatment of hypertensive patients complicated with arrhythmia. 【Methods】 A total of 104 hypertensive patients combined with arrhythmia admitted to our hospital from February 2024 to June 2025 were selected and divided into control group and observation group by random number table method, with 52 cases in each group. The control group received telmisartan tablets combined with metoprolol tartrate tablets tartrate, and the observation group was given Shensong Yangxin Capsule on the basis of the treatment for the control group. The two groups were compared in terms of clinical efficacy, blood pressure [diastolic blood pressure (DBP), systolic blood pressure (SBP)], cardiac function indicators [left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular ejection fraction (LVEF)] and incidence of adverse reactions. 【Results】 The total clinical effective rate of the observation group was 94.23% (49/52), which was higher than 75.00% (39/52) of the control group, and the difference was statistically significant (χ2=7.386, P<0.05). After treatment, DBP and SBP in both groups were lower than those before treatment, and the levels in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). After treatment, LVEDD and LVESD of the two groups were decreased and LVEF was increased compared with those before treatment; LVEDD and LVESD in the observation group were lower, while LVEF was higher than those in the control group, and all differences had statistical significance (all P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (χ2=0.377, P>0.05). 【Conclusion】 Shensong Yangxin Capsule combined with telmisartan tablets and metoprolol tartrate tablets can obviously improve cardiac function of hypertensive patients complicated with arrhythmia, with good clinical efficacy and high safety.
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Received: 24 October 2025
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