心率变异性指标对ACS患者PCI术后短期预后的预测价值

doi:10.3969/j.issn.1671-7171.2026.03.010

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Abstract 【Objective】 To explore the changes of heart rate variability (HRV) indicators in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) treated with oral atorvastatin calcium tablets, and to evaluate the predictive value of HRV indicators in short-term prognosis. 【Methods】 A total of 157 ACS patients who underwent PCI in our hospital from March 2022 to May 2024 were selected. All patients took atorvastatin calcium tablets orally. According to whether major adverse cardiovascular events (MACE) occurred within 6 months after treatment, the patients were divided into a control group (no MACE occurred, n=125) and an observation group (MACE occurred, n=32). HRV indicators [standard deviation of normal-to-normal intervals (SDNN), root mean square of the differences between successive normal-to-normal intervals (rMSSD), low frequency (LF), high frequency (HF), approximate entropy (ApEn), sample entropy (SampEn), SD1, SD2] before and after treatment, 24-hour dynamic electrocardiogram indicators [turbulence slope (TS), turbulence onset (TO), 24-hour QT interval variability (24hQTV), standard deviation of the average normal R-R intervals for successive 5-minute segments (SDANN-index)], and Gensini score were compared between the two groups. Pearson correlation analysis was used to analyze the correlation between Gensini score and HRV indicators, and multivariate Logistic regression analysis was used to analyze the risk factors for MACE in ACS patients. 【Results】 The SDNN, LF, SD2 and Gensini scores in the observation group were higher than those in the control group, while rMSSD, HF and SD1 were lower than those in the control group, with statistically significant differences (P<0.05). The TS, 24hQTV and SDANN-index in the observation group were lower than those in the control group, and TO was higher than that in the control group, with statistically significant differences (P<0.05). Pearson correlation analysis showed that Gensini score was positively correlated with SDNN, LF and SD2 (r=0.266, 0.232, 0.258, all P<0.05), and negatively correlated with rMSSD, HF and SD1 (r=-0.218, -0.181, -0.242, all P<0.05). Multivariate Logistic regression analysis showed that SDNN, LF and SD2 were positively correlated with the risk of MACE in ACS patients (P<0.05), while rMSSD, HF, SD1, 24hQTV and SDANN-index were negatively correlated with the risk of MACE (P<0.05). 【Conclusion】 HRV has high value in predicting the short-term prognosis of ACS patients after PCI, and it plays an important role in evaluating the severity of patients' condition and treatment effect.

Key words： Coronary Artery Disease Acute Disease Syndrome Percutaneous Coronary Intervention Heart Rate

Received: 09 December 2025

PACS:

R543.31

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	XIA Yilan
	YANG Weiya
	SUN Ling

Cite this article:

XIA Yilan,YANG Weiya,SUN Ling. Application Value of Heart Rate Variability Indicators in Predicting Short-Term Prognosis of ACS Patients after PCI[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 387-390.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.03.010 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I3/387

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