血府逐瘀丸联合常规治疗对卵巢癌术后化疗患者疼痛及睡眠质量的影响

doi:10.3969/j.issn.1671-7171.2025.08.008

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Abstract 【Objective】 To explore the effect of Xuefu Zhuyu Pills combined with conventional treatment on pain, sleep quality, cancer-related fatigue, and emotional state in patients with ovarian cancer undergoing postoperative chemotherapy.【Methods】 A total of 86 patients with ovarian cancer receiving postoperative chemotherapy were randomly divided into two groups, with 43 cases in each group. All patients received conventional anti-tumor and symptomatic supportive treatment, and the observation group was additionally given Xuefu Zhuyu Pills. Changes in pain intensity [Visual Analogue Scale (VAS)], sleep quality [Pittsburgh Sleep Quality Index (PSQI)], cancer-related fatigue (Chinese version of the Revised Piper Fatigue Scale score), and emotional state [Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS) scores] were compared between the two groups before and after intervention.【Results】 After 2 and 3 cycles of chemotherapy, the VAS scores in the observation group were significantly lower than those in the control group (P<0.05). After the end of chemotherapy, the PSQI score in the observation group was significantly lower than that in the control group (P<0.05). The scores of all items in the Piper Fatigue Scale, SDS, and SAS in both groups were lower than those before chemotherapy (P<0.05), and the observation group had lower scores than the control group (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).【Conclusion】 Xuefu Zhuyu Pills combined with conventional treatment can effectively relieve pain, improve sleep quality, reduce cancer-related fatigue, and alleviate negative emotions such as depression and anxiety in patients with ovarian cancer during postoperative chemotherapy, which is worthy of clinical promotion and application.

Key words： Ovarian Neoplasms Drug Therapy Pain Sleep

Received: 21 April 2025

PACS:

R737.31

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	Articles by authors
	FENG Guiyang
	ZHANG Xiaotian
	ZHANG Suping

Cite this article:

FENG Guiyang,ZHANG Xiaotian,ZHANG Suping. Effect of Xuefu Zhuyu Pills on Pain and Sleep in Patients with Ovarian Cancer Undergoing Postoperative Chemotherapy[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1321-1323.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.08.008 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I8/1321

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