医学临床研究
   Jun. 18, 2025    Home  |  About Journal  |  Editorial Board  |  Instruction  |  Subscribe  |  Advertisement  |  Messages Board  |  Contact Us  |  中文
JOURNAL OF CLINICAL RESEARCH  2025, Vol. 42 Issue (4): 670-672    DOI: 10.3969/j.issn.1671-7171.2025.04.031
Original Articles Current Issue | Archive | Adv Search |
Correlation Analysis of Blood Biochemical Indicators and Kidney Injury in Patients with Diabetes and Hypertension
ZHAO Liqin, CHEN Fangfang
Department of Laboratory, Meixian People's Hospital, Baoji Shaanxi 722300
Download: PDF (1158 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  【Objective】 To explore the correlation between blood biochemical indicators and kidney injury in patients with diabetes combined with hypertension.【Methods】 A total of 320 patients with diabetes combined with hypertension were divided into a non-injury group (152 cases) and a kidney injury group (168 cases) based on the presence or absence of kidney injury. All patients underwent relevant blood biochemical tests, and the correlation between various indicators and the occurrence of kidney injury was analyzed. Multi-factor logistic regression was used to identify the influencing factors.【Results】 There was no significant difference in fasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPG), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) between the two groups (P>0.05). The levels of glycated hemoglobin (HbA1c), cystatin C (cys C), serum creatinine (Scr), and serum β2-microglobulin (β2-MG) in the kidney injury group were higher than those in the non-injury group (P<0.05). Serum HbA1c, cys C, Scr, and β2-MG levels were positively correlated with the occurrence of kidney injury in patients with diabetes combined with hypertension (P<0.05). Logistic regression analysis showed that HbA1c, cys C, Scr, and β2-MG levels were important influencing factors for the occurrence of kidney injury (OR>1, P<0.05).【Conclusion】 Serum levels of HbA1c, cys C, Scr, and β2-MG are significantly positively correlated with the occurrence of kidney injury in patients with diabetes combined with hypertension, and these indicators are important influencing factors for occurrence of kidney injury, which can provide reference for clinical practice.
Key wordsDiabetes Mellitus      Hypertension      Kidney Injury      Correlation of Data     
Received: 23 October 2024     
PACS:  R587.1  
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
ZHAO Liqin
CHEN Fangfang
Cite this article:   
ZHAO Liqin,CHEN Fangfang. Correlation Analysis of Blood Biochemical Indicators and Kidney Injury in Patients with Diabetes and Hypertension[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(4): 670-672.
URL:  
http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.04.031     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I4/670
Copyright © Editorial Board of JOURNAL OF CLINICAL RESEARCH
Supported by:Beijing Magtech