先天性颗粒细胞牙龈瘤的临床影像特征分析<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2025.02.006

Abstract
Figure/Table
References (16)
Related Citation (15)

Download: PDF (1853 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】To analyze the clinical and imaging finding of in congenital granular cell epulis, and improve the recognition of the disease.【Methods】The clinical data of 6 children diagnosed with CGCE by surgical pathology from June 2017 to February 2023 in our hospital were retrospectively analyzed, and their clinical and imaging characteristics were analyzed.【Results】The maximum tumor diameter of 6 cases was 1.3-3.4 cm, and 4 cases had multiple lesions, of which 3 cases involved both maxillary and mandibular alveolar crista, and 1 case involved both maxillary alveolar crista and sublingual. 2 cases had single lesions involving maxillary anterior alveolar ridge and mandibular alveolar ridge, respectively. Necrosis、cystic change and hemorrhage was not seen in 6 cases. Two cases showed filling enhancement from the edge to the center, and 3 cases showed gradual enhancement. The tumors had high signal on DWI, and low signal on ADC map. No adjacent bone was involved in 6 cases.【Conclusions】The imaging findings of CGCE have certain characteristics, and the diagnosis needs to be confirmed by pathological and immunohistochemical examination.

Key words： Gingival Neoplasms Infant, Newborn Tomography, Spiral Computed Magnetic Resonance Imaging

Received: 25 December 2023

PACS:

R788.3

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.02.006 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I2/197

[1] 成智文, 陈理华. 先天性颗粒细胞牙龈瘤的诊治进展[J].医学综述,2021,27(17): 3456-3459.
[2] TORRESANI E, GIROLAMI I, MARLETTA S, et al. Congenital granular cell epulis of newborn: importance of prenatal diagnosis[J].Pathologica,2021,113(4): 280-284.
[3] AVALOS H S, MANCI E, MULEKAR M, et al. Congenital granular cell epulis: 24 new cases with more differences than similarities to granular cell tumor[J].Ultrastruct Pathol,2022,46(4): 388-400.
[4] 陈瑞琦, 黄卫亮, 张勇, 等. 先天性颗粒细胞牙龈瘤1例[J].中国临床案例成果数据库, 2022, 4(1):E06448.
[5] MIZUTANI K, MUKAI M, NAGATSUKA H, et al. Whitish-yellow tumor on its characteristic cut surface: a case report of congenital granular cell epulis[J].Clin Pathol,2019, 12: 2632010X19831257.
[6] 程龙, 付坤, 高宁, 等. 先天性颗粒细胞龈瘤的临床病理特点及鉴别诊断初探[J].中华口腔医学杂志, 2022, 57(4):410-414.
[7] CONRAD R, PEREZ M C. Congenital granular cell epulis[J].Arch Pathol Lab Med,2014, 138(1): 128-131.
[8] QIN Y L, HU N N, ZHANG C M, et al. Multiple congenital granular cell epulis involving different parts of the oral cavity: a case report[J].Ear Nose Throat J,2024,18:1455613241241106.
[9] 熊飞, 赵朋娜, 赵晓芬. 先天性颗粒细胞牙龈瘤1例[J].中华新生儿科杂志, 2023,38(3):184-185.
[10] LIANG Y, YANG Y S, ZHANG Y. Multiple congenital granular cell epulis in a female newborn: a case report[J].J Med Case Rep,2014, 8: 413.
[11] APARNA H G, JAYANTH B S, SHASHIDARA R, et al. Congenital epulis in a newborn: a case report, immunoprofiling and review of literature[J].Ethiop J Health Sci,2014, 24:359-362.
[12] 牛俊霞, 张焱, 程敬亮. 先天性颗粒细胞牙龈瘤1例[J].中国医学影像技术, 2021, 37(12):1808.
[13] 梁栋,周博,李娜,等. 先天性血管瘤40例临床病理学特征研究[J].中华病理学杂志,2022,51(3):202-206.
[14] HOURANI R, TASLAKIAN B, SHABB N S, et al. Fibroblastic and myofibroblastic tumors of the head and neck: Comprehensive imaging-based review with pathologic correlation[J].Eur J Radiol,2015, 84 (2): 250-260.
[15] YE Y J, TANG R Q, LIU B B, et al. Prenatal diagnosis and multidisciplinary management: A case report of congenital granular cell epulis and literature review[J].J Int Med Res,2021, 49(10): 3000605211053769.
[16] DE STEFANO S, NADAL LÓPEZ E, SABAS M. Congenital epulis: A rare head and neck tumor in the newborn[J].J Craniofac Surg,2023, 34(6): 1741-1743.