|
|
Clinical Effect of Huatan Quyu Recipe on Acute Attack of Migraine with Type of Phlegm Turbidity and Blood Stasis |
LI Maolin, LIU Yanju |
Internal Medicine of Chinese Medicine Department, Xi'an Beilin District Hospital of Traditional Chinese Medicine, Xi'an Shaanxi 710001 |
|
|
Abstract 【Objective】To investigate the clinical effect of Chinese medicine Huatan Quyu decoction on acute attack of migraine with phlegm turbidity and blood stasis type. 【Methods】 A total of 110 patients with migraine admitted to Xi'an Beilin District Hospital of Traditional Chinese Medicine(TCM) were randomly divided into the observation group and the control group with 55 cases each. The patients in the observation group were treated with Huatan Quyu decoction,while the patients in the control group were treated with oral Sibirin. The clinical efficacy, TCM symptom score, hemorheology index, TCD test and the incidence of adverse reactions between the two groups were compared. 【Results】The total clinical effective rate in the observation group was 94.54%, which was higher than that of 81.82% in the control group(P<0.05). After treatment, the plasma specific viscosity, whole blood specific viscosity, hematocrit levels in the observation group were lower(P<0.05). The TCM syndrome score in the observation group after treatment was also lower than that in the control group after treatment(P<0.05). The average blood flow velocity of anterior cerebral artery(ACA), the middle cerebral artery(MCA), posterior cerebral artery(PCA) in the two groups were lower than that before treatment (P<0.05). While The levels of MCA, ACA and PCA in the observation group were lower than that in the control group (P<0.05). The incidence of adverse reactions in the two groups was not statistically different(P>0.05).【Conclusion】Huatan Quyu decoction has a good clinical effect on migraine patients of phlegm turbidity and blood stasis type. It can effectively relieve the clinical symptoms of migraine, reduce blood viscosity, improve brain blood oxygen supply, and has high safety, which is worthy of clinical promotion.
|
Received: 11 May 2022
|
|
|
|
|
[1] 蔡依妏, 裴建, 傅勤慧, 等. 电针四关穴治疗肝阳上亢型偏头痛:随机对照试验[J].中国针灸, 2022, 42(5):498-502. [2] 韩玉晶, 陈彦. 化痰降逆方治疗痰浊型偏头痛的临床疗效观察[J].中西医结合心脑血管病杂志, 2018, 16(20):3065-3066. [3] 吉贞料, 卢桂兰, 王高岸. 通络清空汤辨治偏头痛急性发作期的疗效及作用机制[J].中国实验方剂学杂志, 2016,25(19):154-158. [4] 郑筱萸. 中药新药临床研究指导原则[M].中国医药科技出版社, 2002,34(2):309-312. [5] 中国卒中学会卒中与眩晕分会, 中国医师协会神经内科医师分会眩晕专业委员会. 前庭性偏头痛诊疗多学科专家共识[J].中华内科杂志, 2019, 58(2):102-107. [6] 潘殿卿, 何新霞. 海德克胶囊治疗偏头痛的疗效判定和TCD研究[J].脑与神经疾病杂志, 1997, 5(2):90-93. [7] 潘旭, 倪岚. 中西医结合治疗合并足底按摩疗法治疗痰浊瘀血型偏头痛60例临床观察[J].中西医结合心血管病杂志(电子版), 2017, 5(32):180. [8] 陈兰兰, 徐俊, 于海龙,等. 偏头痛先兆的临床表现及机制的研究进展[J].临床神经病学杂志, 2017, 30(3):224-226. [9] 秦合伟, 李彦杰, 李斯锦,等. 化痰祛瘀中药抗动脉粥样硬化的作用机制研究[J].北京中医药大学学报, 2019,42(7):566-576. [10] 具星, 贾连群, 张哲,等. 益气健脾化瘀祛痰方对脾虚痰浊动脉粥样硬化巴马小型猪心脏线粒体蛋白质组的影响[J].中华中医药杂志, 2017,34(8):3659-3662. [11] 吕春梅, 赵伟伟, 李然,等. 中药方剂胃肠舒组方及其成分药灌胃SD大鼠的胃肠动力观察[J].山东医药, 2019,26(1):142-144. [12] 陈云坤, 王杰, 刘煌. 清热化痰祛瘀方治疗AECOPD(痰热瘀肺证)患者的疗效观察[J].中国中医急症, 2020, 29(5):820-822. [13] 冯利, 庄安琪, 李轶维, 等. 基于网络药理学和体外研究探究瓜蒌薤白半夏汤治疗动脉粥样硬化的机制[J].中国药理学通报,2022,38(6):904-912. [14] 向璐, 张巧艳, 赵琦明, 等. 黄芪-当归化学成分、药理作用及临床应用的研究进展[J].中草药,2022,53(7):2196-2213. |
|
|
|