|
|
|
| Analysis of Risk Factors for Placental Abruption in Pregnant Women with Gestational Hypertension |
| WANG Wei, JIA Bao-ling |
| Department of Obstetrics and Gynecology,Lantian County People's Hospital,Lantian Shaanxi 710500 |
|
|
|
|
Abstract 【Objective】To explore the risk factors of placental abruption in pregnant women with hypertensive disorder complicating pregnancy (HDCP). 【Methods】 A total of 80 HDCP pregnant women admitted to the Obstetrics and Gynecology Department of the Lantian County People's Hospital from July 2018 to July 2021 were selected and divided into early exfoliation group (n=12) and non early exfoliation group (n=68) based on the examination results after admission. The age,pre pregnancy body mass index (BMI),weight gain during pregnancy,history of diabetes,number of pregnant fetuses,history of cesarean section,history of abortion,family history of hypertension,educational level and renal function index [serum urea nitrogen,serum creatinine,uric acid level,glomerular filtration rate] of the two groups were compared,Multiple regression analysis was used to identify the risk factors for placental abruption in HDCP pregnant women. 【Results】There was no significant difference in age,diabetes,multiple pregnancy,cesarean section,abortion,smoking,education,and serum urea nitrogen between the two groups (P>0.05); The pre pregnancy BMI,gestational weight gain,and glomerular filtration rate of the early exfoliation group were lower than those of the non early exfoliation group,while the proportion of individuals with a family history of hypertension,serum creatinine,and uric acid levels were higher than those of the non early exfoliation group (P<0.05). The ROC curve analysis results show that pre pregnancy BMI,gestational weight gain,serum creatinine,uric acid,and glomerular filtration rate can all predict the occurrence of placental abruption in HDCP pregnant women,with areas under the curves of 0.713,0.879,0.849,0.686,and 0.846,respectively. The results of multivariate analysis showed that pre pregnancy BMI<23.51 kg/m2,pregnancy weight gain<14.10 kg,family history of hypertension,and serum creatinine ≥ 66.13 μmol/L,uric acid ≥361.34 μmol/L and glomerular filtration rate<111.86 mL/min were risk factors for placental abruption in HDCP pregnant women (P<0.05). 【Conclusions】The impact of pre pregnancy BMI,gestational weight gain,family history of hypertension,serum creatinine,uric acid,and glomerular filtration rate on placental abruption in HDCP pregnant women needs to be strengthened in clinical practice to prevent the occurrence of placental abruption.
|
|
Received: 06 October 2022
|
|
|
|
|
|
[1] 刘润萍,张格.低剂量阿司匹林联合降压治疗妊娠期高血压疾病对患者凝血指标的影响[J].医学临床研究,2023,40(4):615-618.
[2] 阳子兑娣.妊娠期高血压并发胎盘早剥96例临床分析[J].陕西医学杂志,2016,45(5):574-576.
[3] 中华医学会妇产科学分会妊娠期高血压疾病学组.妊娠期高血压疾病诊治指南(2015)[J].中华妇产科杂志,2015,50(10):721-728.
[4] 中华医学会妇产科学分会产科学组.胎盘早剥的临床诊断与处理规范(第1版)[J].中华妇产科杂志,2012,47(12):957-958.
[5] 龙娅静,张卫萍.妊娠期高血压疾病并发胎盘早剥与母婴不良预后的关系[J].医学综述,2015,21(11):2069-2070.
[6] 蒋锴凯,李青,于慧.妊娠期高血压疾病与胎盘早剥的相关性分析[J].中国妇幼保健,2018,33(24):5784-5786.
[7] 王娜娜,唐增军,于璨,等. 妊娠期高血压疾病患者发生胎盘早剥预测模型的建立与评价[J].现代妇产科进展,2020,29(10):752-755.
[8] 陈敦金,余琳. 妊娠期高血压疾病与胎盘早剥[J].实用医学杂志,2006,22(23):2698-2699.
[9] 宋迎春,朱冰冰,张丹. 妊娠期高血压疾病并发胎盘早剥37例分析[J].中国误诊学杂志,2009,9(19):4724-4725.
[10] 何云. 妊娠中晚期胎盘血管化参数与妊娠期高血压疾病患者不良妊娠结局的关系研究[J].中国计划生育和妇产科,2019,11(4):45-48.
[11] 赵雪峰,杨万杰. 妊娠期高血压疾病严重并发症的研究进展[J].医学综述,2015,21(12):2209-2211.
[12] 林南娟.重度子痫前期并发胎盘早剥的临床分析[J].实用医学杂志,2009,25(16):2733-2734.
[13] 武军,姬明杰,孙丽君. 基质金属蛋白酶-9与妊娠期高血压疾病及胎盘早剥的关系[J].河北医药,2011,33(3):380-381. |
|
|
|
2023, Vol. 40 
