匹伐他汀钙片治疗糖尿病合并高脂血症老年患者的疗效观察

doi:10.3969/j.issn.1671-7171.2021.07.013

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Abstract 【Objective】To investigate the efficacy and safety of pitavastatin in the treatment of hyperlipidemia with type 2 diabetes mellitus(T2DM) in elderly patients. 【Methods】A total of 83 elderly patients with hyperlipidemia and type 2 diabetes mellitus who admitted to 464 PLA Hospital from May 2016 to April 2019 were enrolled in the study. Lab examinations such as liver, renal and thyroid function were carried out , then the original statins were replaced by pitavastatin. The FPG(fasting glucose),2hPG(2 h postprandial blood glucose), HbAlC(glycosylated hemoglobin), TC and TG(triacylglycerol) levels were compared before and after treatment. 【Results】After treatment with Pravastatin, the levels of FPG, 2hPG, HbA1C, TG and mAlb(urine microalbumin) were further decreased(P<0.05), while CK(creatine kinase) , CKMB(creatine kinase isoenzyme), LDH(lactate dehydrogenase), BUN(urea nitrogen) , SCr(creatinine), ALT(alanine aminotransferase) and T₃(triiodothyronine) did not change significantly, and no adverse reactions occurred during the treatment. 【Conclusion】Efficacy and safety of pitavastatin in elderly men with hyperlipidemia disease and type 2 diabetes mellitus were better. It is worthy of clinical popularization and application.

Key words： Diabetes Mellitus /CO Hyperlipidemias/CO Hydroxymethylglutaryl-CoA Reductase Inhibitors/TU Aged

Received: 25 April 2021

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R587.1

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.07.013 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I7/1008

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