单用功效性护肤品治疗轻中度面部玫瑰痤疮及脂溢性皮炎的多中心临床研究

doi:10.3969/j.issn.1671-7171.2021.01.013

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Abstract 【Objective】To investigate the clinical efficacy of single use of functional skin care products in the treatment of mild to moderate facial rosacea and seborrheic dermatitis.【Methods】Patients with mild to moderate facial rosacea or seborrheic dermatitis with a history of more than one month were recruited from dermatology clinics of 17 hospitals nationwide. They were given facial skin care products alone for 2 weeks, and were followed up once a week. The clinical symptoms (dryness, pruritus, burning) and signs (desquamation, erythema) were scored, and their skin barrier indexes were detected.【Results】A total of 324 subjects completed the trial. The symptoms and signs of dryness, pruritus, burning, desquamation and erythema were significantly improved in the first and second weeks (P<0.01). The effective rates after two weeks of treatment were 84.8%, 85.3%, 91.1%, 78.5% and 46.8% respectively. The TEWL decreased from 13.88 g/(cm²·h) to 11.89 g/(cm²·h), and the water content of stratum corneum increased from 62.96% to 69.88%.【Conclusion】Skin barrier repair milk alone can effectively treat mild to moderate facial rosacea and seborrheic dermatitis by repairing the skin barrier function, reduce the patients' facial skin desquamation and erythema, and relieve their sensitive symptoms, which is worthy of clinical application.

Key words： Rosacea/TH Dermatitis Seborrheic/TH Skin Cream/TU Therapies Investigational

Received: 30 September 2020

PACS:

R758.733

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	Articles by authors
	YANG Xi-zhao
	TANG Yan
	LI Ji
	et al

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YANG Xi-zhao,TANG Yan,LI Ji, et al. A Multicenter Clinical Study on the Treatment of Mild to Moderate Facial Rosacea and Seborrheic Dermatitis with Functional Skin Care Products Alone[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(1): 43-46.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.01.013 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I1/43

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