Abstract 【Objective】To investigate the clinical efficacy of single use of functional skin care products in the treatment of mild to moderate facial rosacea and seborrheic dermatitis.【Methods】Patients with mild to moderate facial rosacea or seborrheic dermatitis with a history of more than one month were recruited from dermatology clinics of 17 hospitals nationwide. They were given facial skin care products alone for 2 weeks, and were followed up once a week. The clinical symptoms (dryness, pruritus, burning) and signs (desquamation, erythema) were scored, and their skin barrier indexes were detected.【Results】A total of 324 subjects completed the trial. The symptoms and signs of dryness, pruritus, burning, desquamation and erythema were significantly improved in the first and second weeks (P<0.01). The effective rates after two weeks of treatment were 84.8%, 85.3%, 91.1%, 78.5% and 46.8% respectively. The TEWL decreased from 13.88 g/(cm2·h) to 11.89 g/(cm2·h), and the water content of stratum corneum increased from 62.96% to 69.88%.【Conclusion】Skin barrier repair milk alone can effectively treat mild to moderate facial rosacea and seborrheic dermatitis by repairing the skin barrier function, reduce the patients' facial skin desquamation and erythema, and relieve their sensitive symptoms, which is worthy of clinical application.
YANG Xi-zhao,TANG Yan,LI Ji, et al. A Multicenter Clinical Study on the Treatment of Mild to Moderate Facial Rosacea and Seborrheic Dermatitis with Functional Skin Care Products Alone[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(1): 43-46.
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2021, Vol. 38 
