妇科恶性肿瘤患者围术期并发深静脉血栓的危险因素分析

doi:10.3969/j.issn.1671-7171.2021.02.009

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Abstract 【Objective】 To investigate the risk factors of perioperative deep venous thrombosis (DVT) in patients with gynecological malignancies. 【Methods】 In this study, we selected the literatures of gynecological malignant tumor complicated with DVT published from January 2010 to December 2019 for META-analysis to explore the risk factors of gynecological tumor patients complicated with DVT during perioperative period.【Results】 A total of 12 articles were included, with 13 risk factors, including age, body mass index (BMI), operation, chemotherapy, tumor stage, hypertension, history of thrombosis, operation time, blood transfusion, PICC catheterization, hyperlipidemia, diabetes, D-dimer. The statistically significant risk factors were BMI (OR=2.65,95%CI:1.61~4.36, P=0.0001), surgery (OR=2.33, 95%CI:1.62~3.36, P<0.0001), chemotherapy (OR=2.08, 95%CI:1.50~2.90, P<0.0001), tumor stage (OR=2.42, 95%CI:1.54~3.8, P<0.0001), hypertension (OR=3.10,95%CI:2.13~4.50,P<0.0001), blood transfusion (OR=7.19, 95%CI: 2.55~20.30, P=0.0002), PICC catheterization (OR=2.07, 95%CI: 1.38~3.12, P=0.0005), diabetes (OR=3.66 , 95%CI:1.78~7.53,P=0.0004), operation time ≥3 h(OR=1.1, 95%CI: 1.01~1.20, P=0.03). 【Conclusion】 BMI, operation, chemotherapy, tumor stage, hypertension, blood transfusion, PICC catheterization, diabetes, operation time ≥3 h are the risk factors of DVT in the perioperative period of gynecological malignant tumor. It is possible that controlling the above factors can effectively reduce the incidence of DVT.

Key words： Genital Neoplasms, Female Gynecologic Surgical Procedures/AE Laparoscopy Venous Thrombosis/ET Risk Factors

Received: 04 September 2020

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	HU Zheng-zhong
	ZHOU Yi-feng
	PENG Jin
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HU Zheng-zhong,ZHOU Yi-feng,PENG Jin, et al. Risk Factors of Deep Venous Thrombosis in Patients with Gynecological Malignancies during Perioperative Period[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(2): 192-194.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.02.009 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I2/192

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