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| Effect of Ultrasound-guided Paravertebral Nerve Block Anesthesia on Stress Response and Hemodynamics in Patients with Lung Cancer |
| LI Chun-fang, CHENG Long |
| Bazhong Traditional Chinese Medicine Hospital, Department of Anesthesiology, Bazhong, Sichuan, 636000 |
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Abstract 【Objective】 To observe the effect of ultrasound-guided paravertebral nerve block anesthesia on lung cancer patients and its influence on stress index and hemodynamics. 【Methods】 One hundred Patients with lung cancer who underwent surgery from May 2016 to May 2018 in our hospital were selected as the study subjects. According to the different anesthetic methods, the patients in the observation group were given ultrasound-guided paravertebral nerve block anesthesia and patients in the control group received general anesthesia. The effects of anesthesia were observed and the differences of hemodynamics, stress index and immune function were compared between the two groups.【Results】 The Visual simulation (VAS)scores of the patients at both 4h and 12 h after surgery in the observation group were lower than those in the control group ( P<0.05). There was no significant difference in Ramsay scores between the two groups (P>0.05). There was no difference in hemodynamic parameters, immune function and stress index between the two groups before anesthesia. The levels of SBP,MAP,HR and cortisol , TNF-α in the observation group at 4 hours after anesthesia were lower than those in the control group ( P<0.05). At 4 hours after operation, the levels of CD4+ and CD8+ in the observation group were higher than those in the control group (P<0.05).【Conclusion】 Ultrasound-guided paravertebral nerve block anesthesia has a good anesthetic effect for lung cancer patients, and has little effect on hemodynamics and immune function. It has a good application value.
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Received: 11 April 2019
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2020, Vol. 37 
