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| Comparison of Clinical Features and Short- and Long-term Prognosis between Simple Cerebral Infarction and Cerebral Infarction with Metabolic Syndrome |
| LI Guo-feng, WEI Yu-qing, JIA Liang,et al |
| Internal Medicine-Neurology,Xingtai Third Hospital,Hebei Xingtai 054000 |
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Abstract 【Objective】To compare clinical characteristics, short-term and long-term prognosis between simple cerebral infarction and cerebral infarction with metabolic syndrome to explore the related factors of prognosis. 【Methods】The clinical data of 328 patients with cerebral infarction admitted to our hospital from May 2010 to May 2016 were retrospectively analyzed. According to whether or not they had metabolic syndrome, they were divided into the metabolic syndrome complication group (182 cases) and simple cerebral infarction group (146 cases), respectively. The clinical characteristics and short-term and long-term prognosis of the two groups were compared and analyzed. The key factors affecting the short-term and long-term prognosis were discussed by logistic regression analysis. 【Results】There were significant differences in gender, age, BMI, prevalence and classification of hypertension, diabetes mellitus, FBG, Fins, HOMA-IRI, HbA1C, blood lipids, HCY, IMT thickening, TOAST classification, complications and LOS between the two groups (P<0.05). However, there were no significant differences of cerebral infarction sites with smoking and drinking (P>0.05).Compared to the simple cerebral infarction group, the short-term effective rate was significantly lower in the cerebral infarction with metabolic syndrome group, while the long-term disability rate and recurrence rate were significantly higher (P<0.05).The Logistic regression analysis showed that hypertension classification (grade three), HbA1C, TOAST classification (LAA), complications (pulmonary embolism) and metabolic syndrome were the key factors affecting the short-term prognosis of cerebral infarction (P<0.05); IMT thickening, infarction site (occipital lobe), complications (pulmonary embolism) and metabolic syndrome were the key factors affecting cerebral infarction disability (P<0.05),and complications (pulmonary embolism) and metabolic syndrome were the key factors affecting the recurrence of cerebral infarction (P<0.05). 【Conclusion】There are significantly different in terms of clinical characteristics and long-term prognosis in patients with simple cerebral infarction and cerebral infarction complicated with metabolic syndrome. The metabolic syndrome is the key factor affecting the prognosis of cerebral infarction.
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Received: 27 February 2019
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2019, Vol. 36 
