ERα、ERβ在胎膜完整早产产妇蜕膜组织中的表达及其意义

doi:10.3969/j.issn.1671-7171.2019.08.015

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Abstract 【Objective】To investigate the expression and significance of estrogen receptor α (ER α)and estrogen receptor β(ER β) in decidual tissue of premature parturients with intact membranes.【Methods】 20 parturients with complete premature delivery, 20 parturients with full term parturition (positive control group) and 20 parturients without birth sign (negative control group) were selected ,and the expression of ERαand ERβin decidua of the three groups were detected by immunohistochemistry.【Results】The expression rate of ER α in decidua of complete premature delivery group and term parturient group was significantly higher than that of full-term parturient group (P<0.05), and the expression rate of ER β in decidual tissue of complete premature delivery group and term parturient group was significantly lower than that of full-term parturient group (P<0.05), and the expression rate of ER β in decidual tissue of the complete premature delivery group and the full-term parturient group was significantly lower than that of the full-term parturient group (P<0.05). However, there was no significant difference in the positive expression rates of ER α and ER β in decidua between the complete premature delivery group and the term parturient group (P>0.05).【Conclusion】The increase of ER α expression and the decrease of ER β expression in decidual tissue of parturients with complete premature delivery may be one of the causes of premature delivery.

Key words： Decidua/PP Premature Birth

Received: 13 March 2019

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R71

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	YANG Yu-jiao
	SHEN Xiao-jun
	ZHANG Shu-xuan

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YANG Yu-jiao,SHEN Xiao-jun,ZHANG Shu-xuan. Expression and Significance of ERα and ERβ in Decidua of Premature Women with Intact Fetal Membranes[J]. JOURNAL OF CLINICAL RESEARCH, 2019, 36(8): 1498-1500.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2019.08.015 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2019/V36/I8/1498

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